JWH-210

JWH-210 (John William Huffman-210) is a synthetic research chemical belonging to the naphthoylindole class of cannabinoid receptor agonists. First synthesized by the research group of Professor John William Huffman at Clemson University, this compound features a naphthoyl group attached to the indole core at the 3-position and an ethyl substitution on the indole nitrogen. JWH-210 acts as a potent agonist at the CB1 and CB2 cannabinoid receptors, with research indicating high affinity for both receptor subtypes. RChems EU supplies JWH-210 as a high-purity crystalline powder with verified 99%+ purity, ensuring reproducible results for in vitro cannabinoid receptor binding assays, neuropharmacological investigations, and structure-activity relationship (SAR) studies.

Physical and Chemical Properties

• Chemical Name: (4-ethylnaphthalen-1-yl)(1-ethyl-1H-indol-3-yl)methanone

• Molecular Formula: C₂₄H₂₃NO

• Molecular Weight: 341.45 g/mol

• Appearance: White to off-white crystalline powder

• Purity: ≥99% (Verified by HPLC, NMR, MS)

• Solubility: Soluble in organic solvents (ethanol, DMSO); practically insoluble in water

• CAS Number: 824959-81-1

• Storage: Cool, dry, dark environment (room temperature recommended)