Dihexa
€ 80,00 – € 130,00Price range: € 80,00 through € 130,00
Dihexa (N-hexanoic-Tyr-Ile-(6)aminohexanoic amide) is a synthetic, small-molecule neurotropic peptide developed for research into cognitive enhancement, synaptic regeneration, and neurorepair mechanisms. Supplied by RChems EU, a trusted global supplier of 99% pure research chemicals, this compound is widely studied for its ability to bind hepatocyte growth factor (HGF) and activate c-Met signaling pathways—offering unique applications in models of neurodegeneration, traumatic brain injury (TBI), and Alzheimer’s disease research.
Physical and Chemical Properties:
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Appearance: White to off-white lyophilized powder
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Purity: ≥99% (HPLC-MS verified)
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Molecular Formula: C₂₈H₄₄N₄O₅
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Molecular Weight: 516.67 g/mol
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Solubility: Soluble in DMSO, ethanol, and aqueous buffers with pH adjustment
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Peptide Sequence: Hexanoyl-Tyr-Ile-Ahx-NH₂
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Storage: Refrigerated (2–8°C), protected from light and moisture
Buy Dihexa Research Chemical Online USA, Europe and Worldwide
In the frontier of neuroregenerative research, Dihexa stands apart as one of the most potent small-molecule cognitive enhancers identified to date. Unlike traditional nootropic compounds that merely modulate neurotransmitter systems, Dihexa functions as a hepatocyte growth factor (HGF) mimetic, activating the c-Met receptor and promoting synaptogenesis, dendritic branching, and functional recovery in injured neuronal tissue. First characterized by researchers at Washington State University, Dihexa has since become a compound of intense interest for laboratories studying Alzheimer’s disease, traumatic brain injury (TBI), stroke recovery, and age-related cognitive decline.
If you need to buy Dihexa for advanced neuropharmacology or regenerative medicine research, you require a supplier that guarantees analytical-grade purity, global logistics, and absolute discretion. RChems EU delivers exactly that. As a trusted global supplier of 99% pure research chemicals, we provide batch-verified Dihexa to research institutions, pharmaceutical R&D teams, and independent scientists across the USA, Canada, Europe, Australia, and Asia. Every order is backed by rigorous third-party testing, discreet packaging, and fast worldwide delivery.
Key Features & Benefits
- ≥99% Verified Purity – Each batch independently tested using HPLC-MS, NMR, and residual solvent analysis. No degradation products, no synthetic impurities.
- Potent HGF Mimetic – Binds hepatocyte growth factor with high affinity (Kd ~ 1 nM), activating c-Met signaling pathways involved in synaptogenesis and neuronal survival.
- Long-Acting in Research Models – Demonstrated duration of action exceeding 48 hours in preclinical studies, enabling extended dosing intervals in animal models.
- Penetrates Blood-Brain Barrier – Unlike many neurotrophic factors, Dihexa crosses the BBB in animal models without chemical modification.
- Discreet & Secure Shipping – Plain outer packaging, unmarked labels, vacuum-sealed inner bag. No chemical names or supplier branding on the parcel.
- Fast Worldwide Delivery – Express shipping to over 50 countries. Typical transit: 5–9 business days.
- Lot-Specific Certificate of Analysis (CoA) – Available upon request for every batch, documenting purity, mass confirmation, and heavy metal screening.
Product Specifications
| Property | Detail |
|---|---|
| Product Name | Dihexa |
| Synonyms | N-hexanoic-Tyr-Ile-(6)aminohexanoic amide; Dihexa peptide |
| CAS Number | 1318757-41-9 (typical) |
| Purity | >99% (HPLC-MS, area under curve) |
| Chemical Class | Synthetic peptide / HGF mimetic |
| Form | Lyophilized powder (freeze-dried) |
| Molecular Weight | 516.67 g/mol |
| Water Content (KF) | <1.0% |
| Recommended Storage | 2–8°C, desiccated, protected from light |
| Stability | >24 months under proper storage |
Applications & Usage
Dihexa is intended for laboratory research use only. Typical applications include:
- Alzheimer’s Disease Models: Investigating Dihexa’s ability to restore synaptic density and cognitive function in transgenic rodent models (e.g., APP/PS1, 5xFAD) via c-Met activation.
- Traumatic Brain Injury (TBI) Research: Evaluating neurorepair and functional recovery following controlled cortical impact (CCI) or fluid percussion injury models.
- Synaptogenesis Studies: Quantifying dendritic spine density, PSD-95 expression, and synaptic protein turnover in primary hippocampal neuron cultures.
- Stroke & Ischemia Models: Examining neuroprotective and regenerative effects following middle cerebral artery occlusion (MCAO).
- Aging & Cognitive Decline: Assessing age-related deficits in spatial memory (Morris water maze, novel object recognition) in aged rodent models.
- HGF/c-Met Pathway Analysis: Receptor binding assays, phosphorylation studies (c-Met, Akt, ERK), and downstream gene expression profiling.
All studies must comply with institutional animal care and use committee (IACUC) or equivalent ethical guidelines. Not for human or veterinary consumption.
Purity & Testing
Reproducibility in neuroregenerative research depends entirely on compound integrity. Every batch of 99% pure Dihexa from RChems EU undergoes a comprehensive analytical workflow:
- High-Performance Liquid Chromatography (HPLC) – Quantifies main peak purity with UV detection at 214nm and 280nm. Acceptance threshold: ≥99.0% AUC.
- Mass Spectrometry (MS) – Confirms molecular weight (expected [M+H]+ = 517.3) and detects trace-level deletion or insertion peptides.
- Nuclear Magnetic Resonance (NMR) – ¹H and ¹³C NMR validate the hexanoyl modification and the Tyr-Ile-Ahx backbone.
- Residual Solvent Analysis (Gas Chromatography) – Screens for Class 1, 2, and 3 residual solvents per ICH Q3C guidelines.
- Heavy Metals Testing (ICP-MS) – Ensures lead, arsenic, cadmium, mercury, and other toxic metals are below 1 ppm.
- Karl Fischer Titration – Confirms water content <1%, critical for peptide stability.
Why purity matters: Impurities in peptide research can produce false-positive signaling (by activating c-Met non-specifically) or false-negative results (by degrading before receptor binding). When you buy 99% pure Dihexa, you eliminate these variables, ensuring that your data reflects the compound’s true neuroregenerative potential.
Safety & Handling Guidelines
- For professional laboratory use only. Must be handled by trained researchers wearing appropriate PPE (nitrile gloves, lab coat, safety goggles).
- Not for human, animal, or therapeutic use. Do not ingest, inhale, inject, or apply to skin/mucous membranes.
- First aid: Skin contact – wash with soap and water for 15 minutes. Eye contact – rinse with saline or water, seek medical attention if irritation persists. Inhalation – move to fresh air.
- Spill management: Vacuum with HEPA filter or wet-wipe; avoid generating airborne particulates.
- Storage: Keep container tightly sealed in a refrigerator (2–8°C), desiccated, and protected from light. Do not freeze unless reconstituted in appropriate buffer.
- Disposal: Follow institutional hazardous waste protocols; incineration recommended.
Global Shipping & Discreet Delivery
RChems EU understands that confidentiality and delivery speed are as critical as product quality. When you order Dihexa for research, here is exactly what to expect:
Discreet Packaging Protocol:
- Plain outer box – No logos, no brand names, no chemical identifiers.
- Unmarked shipping label – Generic return address (e.g., “Logistics Fulfillment Center”).
- No external documentation – Invoices and CoAs are emailed only.
- Vacuum-sealed inner bag – Eliminates moisture ingress, prevents contamination, and adds tamper evidence.
- Opaque inner wrap – Contents cannot be identified even if outer box is damaged.
- Thermal insulation for peptides – Refrigerated shipping available upon request (additional fee).
Fast Worldwide Delivery:
- United States & Canada: 5–7 business days (Express courier: UPS / FedEx).
- Europe (EU & UK): 4–6 business days (DHL Express).
- Australia & New Zealand: 7–9 business days.
- Asia (Japan, Singapore, South Korea): 6–8 business days.
- Rest of World: 10–12 business days (subject to customs).
Tracking numbers provided within 24 hours of dispatch. We offer reshipment or refund for legitimate non-delivery or customs seizure (excluding regions where Dihexa is explicitly banned).
Why Choose RChems EU?
- Verified 99%+ Purity – Every batch tested via HPLC-MS, NMR, GC, and ICP-MS. CoA available on request.
- Stealth, Discreet Packaging – Plain boxes, unmarked labels, no chemical names on parcel. Maximum privacy guaranteed.
- Fast Global Shipping – Express delivery to the USA, Europe, and worldwide. Tracking included.
- Peptide Stability Expertise – Proper lyophilization and vacuum-sealing ensure your Dihexa arrives intact.
- Responsive Scientific Support – Research-grade inquiries answered within 24 hours.
- No Minimum Order – Single milligrams available for pilot studies; bulk discounts for institutions.
- Secure Payments – Cryptocurrency (BTC, ETH) and credit card options.
We are not a reseller or marketplace. We are a trusted global supplier of 99% pure research chemicals, and Dihexa is one of our most advanced neuroregenerative research compounds.
Legal & Safety Disclaimer
IMPORTANT: Dihexa is sold strictly for research and laboratory use only. It is not a drug, medicine, food additive, dietary supplement, or therapeutic agent. It is not for human consumption, animal treatment, or any clinical application. By placing an order, you affirm that you are at least 18 years of age and that you will comply with all applicable local, state, and federal laws regarding the purchase, import, and handling of research chemicals. RChems EU reserves the right to cancel any order where local regulations prohibit Dihexa. Do not buy Dihexa unless you are a qualified researcher in a properly equipped laboratory.
FAQ Section
1. What is Dihexa used for in research?
Dihexa is a synthetic peptide studied for its ability to mimic hepatocyte growth factor (HGF) and activate c-Met receptor signaling. Researchers use Dihexa in models of Alzheimer’s disease, traumatic brain injury (TBI), stroke recovery, and age-related cognitive decline to investigate synaptogenesis, dendritic regeneration, and functional neurorepair. It is not for human or veterinary use.
2. Is Dihexa legal to buy and import?
Legality varies by jurisdiction. In the United States, Dihexa is not a DEA-controlled substance and is generally considered a research chemical. However, some countries may have restrictions on peptide-based cognitive enhancers. You are solely responsible for verifying local laws before ordering. RChems EU will not be liable for customs seizures.
3. How discreet is shipping from RChems EU?
Completely discreet. Your package arrives in a plain, unmarked cardboard box with no branding, no logos, and no mention of “Dihexa,” “peptide,” or “research chemical.” The shipping label shows only a generic return address. Inside, the product is vacuum-sealed in an opaque, moisture-proof bag. No invoice or chemical name appears on the exterior.
4. What is the purity level of your Dihexa?
Every batch is independently tested and confirmed at ≥99% purity via HPLC-MS and NMR. We provide a lot-specific Certificate of Analysis (CoA) upon request. Residual solvents, water content, and heavy metals are also screened to ensure research-grade quality.
5. How is purity tested?
Our purity protocol includes:
- HPLC for quantitative main peak purity (>99%)
- Mass Spectrometry for molecular weight confirmation (517.3 m/z [M+H]+)
- NMR (¹H & ¹³C) for structural verification of the hexanoyl-Tyr-Ile-Ahx sequence
- Gas Chromatography for residual solvents
- Karl Fischer Titration for water content (<1%)
- ICP-MS for heavy metals (Pb, As, Cd, Hg)
All data is archived and traceable by batch number.
6. How should I store Dihexa for research?
Store Dihexa as a lyophilized powder at 2–8°C (refrigerator), protected from light and moisture. Do not freeze the dry powder. Once reconstituted in DMSO or buffer, aliquot and store at -20°C to -80°C; avoid repeated freeze-thaw cycles. Properly stored, the dry powder remains stable for 24+ months.
7. Does Dihexa cross the blood-brain barrier (BBB)?
Yes. In preclinical research models, Dihexa has demonstrated the ability to cross the BBB without chemical modification, a key advantage over many neurotrophic factors (e.g., BDNF, NGF) that require invasive delivery methods. This property makes Dihexa particularly valuable for oral or systemic administration studies in animal models.
8. Can I track my worldwide delivery?
Yes. All orders receive a tracking number via email within 24 hours of shipment. You can monitor your package in real time through DHL, FedEx, or UPS (depending on destination). Delivery to the USA or Europe typically takes 5–7 business days.
9. Do you offer reshipment if customs seizes my order?
We offer one free reshipment or a 50% refund for orders seized by customs in countries where Dihexa is not explicitly prohibited. You must provide official customs documentation. No reshipment is offered to jurisdictions where this compound is banned. Always check local laws before you buy Dihexa.
For bulk pricing, CoA requests, or research inquiries, contact RChems EU directly via the website.
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