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Ro5-4864
(4′-Chlorodiazepam / 7-chloro-5-(4-chlorophenyl)-1-methyl-3H-1,4-benzodiazepin-2-one)
represents a uniquely structured and highly specialized benzodiazepine derivative. Renowned across neurochemical literature for its selective binding profile, this high-purity compound stands out as an indispensable subject for cutting-edge spectroscopic, structural, metabolic, and receptor-binding analytical investigation. When researchers choose to Buy Ro5-4864 Online, they secure an essential tool for advanced laboratory testing.
Featuring a characteristic 4′-chloro modification on the 5-phenyl ring paired with the classical 1,4-benzodiazepine core, this compound acts as a classic ligand for the translocator protein (TSPO), formerly known as the peripheral benzodiazepine receptor (PBR). It delivers a remarkably distinct chemical profile compared to central GABA-A receptor ligands, making it an exceptional standard for comparative laboratory profiling, quantitative assay calibration, and subcellular transport studies. Secure your batch today when you decide to Buy Ro5-4864 Online to guarantee reproducible, consistent, and verifiable analytical results for your ongoing laboratory projects.
Chemical Identification & Technical Specifications
Comprehensive structural verification and reliable chemical data are fundamental to successful laboratory testing. Below is the detailed technical profile for high-purity Ro5-4864 reference material available for verified research facilities:
| Product Name | Ro5-4864 |
| Systematic / Alternative Name | 4′-Chlorodiazepam (7-Chloro-5-(4-chlorophenyl)-1-methyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one) |
| Full IUPAC Description | 7-chloro-5-(4-chlorophenyl)-1-methyl-3H-1,4-benzodiazepin-2-one |
| Molecular Formula | C₁₆H₁₂Cl₂N₂O |
| Molar Mass | 319.18 g/mol |
| Availability Status | In Stock – Ready for Immediate Worldwide Dispatch |
*Every single order is backed by full analytical documentation, including batch-specific testing protocols to guarantee optimal purity and precision in experimental application.
Why Choose Ro5-4864? Molecular & Structural Advantage
When expanding your chemical research portfolio, optioning to Buy Ro5-4864 Online offers a distinctive comparative advantage over classical central benzodiazepine receptor agonists like Diazepam or Nitrazepam. By introducing a single chlorine substituent at the para-position (4′) of the 5-phenyl ring, its affinity shifts dramatically away from central GABA-A ion channel complexes and toward mitochondrial translocator proteins (TSPO).
This targeted structural divergence alters electronic parameters and receptor selectivity significantly, offering distinct operational features for bioanalytical assays and comparative profiling:
Standard Diazepam
Features an unsubstituted 5-phenyl ring structure—primarily targeting central GABA-A receptors with minimal selectivity for peripheral mitochondrial complexes.
Advanced Ro5-4864 (4′-Chlorinated)
Para-chloro modification yields nanomolar affinity for TSPO/PBR, providing essential reference spectra for mitochondrial membrane research and specialized HPLC retention analysis.
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Experimental precision matters above all else. We supply fully characterized research materials complete with batch-specific certificates of analysis (CoA), High-Performance Liquid Chromatography (HPLC) profiles, Nuclear Magnetic Resonance (NMR) spectra, and Mass Spectrometry (MS) validation.
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Key Product Highlights
Ro5-4864 (4′-Chlorodiazepam)
7-chloro-5-(4-chlorophenyl)-1-methyl-3H-1,4-benzodiazepin-2-one
1,4-Benzodiazepine Derivative
C₁₆H₁₂Cl₂N₂O
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Explore Additional Research Chemical Resources
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Very effective, exactly as described for research purposes