2F-DCK 50 MG Pellets

Buy 2F-DCK 50 MG Pellets Research Chemical Online – USA, Europe & Worldwide

The arylcyclohexylamine class of research chemicals has been instrumental in advancing our understanding of NMDA receptor pharmacology. 2F-DCK (2-fluorodeschloroketamine) is a structural analog of the well-known dissociative anesthetic ketamine, distinguished by the replacement of the 2-chloro group with a fluorine atom. This fluorinated modification alters the compound’s electronic properties, metabolic stability, and receptor interaction kinetics, making it a valuable tool for structure-activity relationship (SAR) studies.

For researchers conducting repetitive dose-response studies or requiring standardized sample preparation, the pre-dosed 50 mg pellet format offers significant advantages over powdered research chemicals. The pre-dosed format eliminates the need for analytical balance weighing, reduces inter-sample variability, and streamlines laboratory workflows. When you buy 2F-DCK 50 mg pellets from RChems EU, you acquire a high-purity research compound in a convenient, pre-dosed format. Our 99% pure 2F-DCK pellets are intended exclusively for laboratory research—not for human or animal consumption—enabling precise, reproducible experiments in receptor pharmacology, neurochemistry, and behavioral neuroscience.

Key Features & Benefits

• Pre-Dosed 50 mg Format: Eliminates need for manual weighing, reduces measurement error, and saves valuable laboratory time.
• Verified 99%+ Purity: Every batch of active ingredient undergoes independent HPLC, LC-MS, and ¹H/¹³C NMR analysis.
• Fluorinated Ketamine Analog: The 2-fluoro substitution enables SAR studies comparing halogen effects (F vs. Cl) on NMDA receptor binding and metabolic stability.
• Arylcyclohexylamine Research Tool: Potent NMDA receptor antagonist for studying glutamatergic neurotransmission and dissociative phenomena.
• Homogeneous Dosage Units: Consistent 50 mg per pellet ensures reproducible sample preparation across multiple experiments.
• Reduced Variability: Pre-dosed format minimizes inter-operator and inter-experiment weighing variability.
• Enhanced Stability: Pellet formulation protects the active compound from degradation.
• Worldwide Delivery: Fast, tracked shipping to the USA, Canada, Europe, Australia, and select Asian research hubs.
• Discreet Packaging Protocol: Plain outer boxes, unmarked labels, vacuum-sealed inner bags—no chemical names on the parcel.

Product Specifications

Property	Specification
Active Ingredient	2F-DCK (2-Fluorodeschloroketamine)
Dosage Form	Homogeneous solid pellets
Pellet Strength	50 mg of 2F-DCK per pellet
Active Purity	≥99% (Verified by HPLC, NMR, MS)
Molecular Formula	C₁₃H₁₆FNO
Molecular Weight	221.27 g/mol (freebase)
Pellet Appearance	Uniform, solid cylindrical pellets
Storage	Cool, dry, dark environment (room temperature)
Chemical Class	Arylcyclohexylamine / NMDA receptor antagonist

Applications & Usage

⚠️ Strictly for laboratory research use only. Not for human or animal consumption.

2F-DCK 50 mg pellets are utilized in a range of non-clinical, pre-clinical, and basic science research applications where pre-dosed formats offer advantages over powdered chemicals. Typical areas of investigation include:

• Dose-Response Studies: The pre-dosed 50 mg pellets enable consistent, repeatable dosing across multiple experimental replicates, reducing inter-sample variability.
• NMDA Receptor Binding Assays: After dissolution of the pellet in appropriate solvent (ethanol or DMSO), researchers can evaluate affinity (Ki) for the phencyclidine (PCP) binding site within the NMDA receptor ion channel using radioligand displacement (e.g., [³H]MK-801 or [³H]TCP) in rat brain homogenates or transfected cell lines.
• Ion Channel Functional Studies: Measuring NMDA receptor-mediated calcium influx or electrophysiological recordings (patch-clamp) to assess the potency and efficacy of channel blockade.
• Structure-Activity Relationship (SAR) Investigations: Systematically comparing 2F-DCK with ketamine (2-chloro), deschloroketamine (no halogen), and other fluorinated arylcyclohexylamines to map the impact of halogen substitution on NMDA receptor affinity, selectivity, and use-dependent block kinetics.
• Glutamatergic Neurotransmission Research: Investigating the role of NMDA receptors in synaptic plasticity, long-term potentiation (LTP), and excitotoxicity using in vitro brain slice preparations or neuronal cell cultures.
• Metabolic Stability Research: Evaluating phase I metabolism using hepatic microsomes or S9 fractions with LC-MS/MS quantification, studying the impact of fluorine substitution on oxidative metabolism.
• Analytical Reference Standard Preparation: Pellets can be dissolved to prepare calibrated solutions for forensic toxicology, wastewater analysis, or NPS screening methods.
• In Vitro Neurotoxicity Screening: Assessing cytotoxicity, mitochondrial function, and oxidative stress markers in neuronal cell cultures (e.g., cortical neurons, SH-SY5Y cells).

Researchers are encouraged to consult peer-reviewed literature (e.g., Journal of Pharmacology and Experimental Therapeutics, Neuropharmacology, European Journal of Pharmacology, ACS Chemical Neuroscience) for established in vitro protocols. RChems EU does not provide research protocols but guarantees the compound’s structural integrity and purity for such applications.

Purity & Testing

Reproducibility in NMDA receptor pharmacology and neuropharmacology research depends critically on compound purity. The active ingredient in each 2F-DCK 50 mg pellet is subjected to rigorous independent testing before pelletization. Impurities—particularly other arylcyclohexylamine isomers, synthetic intermediates, or degradation products—can produce false-positive signals in receptor binding assays or confound functional readouts. That is why 99% pure 2F-DCK is the foundation of every pellet from RChems EU:

1. Active Ingredient Testing (Pre-Pelletization):
   • High-Performance Liquid Chromatography (HPLC-DAD): Quantitative analysis at multiple wavelengths. Minimum acceptance criterion: ≥99.0% peak area purity.
   • Liquid Chromatography-Mass Spectrometry (LC-MS): Confirms molecular ion [M+H]⁺ = 222.1 and detects trace-level organic impurities down to 0.05%.
   • Nuclear Magnetic Resonance (NMR): Both proton (¹H) and carbon-13 (¹³C) NMR verify the correct cyclohexanone ring system, N-methyl group, and 2-fluoro substitution pattern on the phenyl ring (characteristic aromatic fluorine coupling patterns).
   • Residual Solvent Analysis (GC-MS): Ensures compliance with ICH limits.
   • Heavy Metal Testing (ICP-MS): Confirms levels below 20 ppm.
2. Post-Pelletization Quality Control:
   • Homogeneity Testing: Randomly selected pellets are assayed to confirm consistent 50 mg ±5% active content.
   • Disintegration Testing: Pellets are tested for dissolution in standard laboratory solvents (ethanol, DMSO) to ensure complete release of active compound.

Each batch is assigned a unique lot number, and a Certificate of Analysis (COA) for the active ingredient is available upon request. This rigorous testing ensures that when you

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 for research, you receive a consistent, high-precision product.

Safety & Handling Guidelines

⚠️ FOR LABORATORY RESEARCH USE ONLY. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

• Personal Protective Equipment (PPE): Always wear nitrile gloves, a lab coat, and chemical splash goggles when handling pellets or preparing solutions.
• Engineering Controls: Use a certified chemical fume hood or glove box when dissolving pellets or handling the active compound in solution.
• First Aid Measures:
  • Inhalation: Remove to fresh air. If breathing difficulty persists, seek medical attention.
  • Skin Contact: Wash with soap and copious water for 15 minutes. Remove contaminated clothing.
  • Eye Contact: Rinse cautiously with water for 15 minutes. Consult an ophthalmologist if irritation persists.
  • Ingestion: Do NOT induce vomiting. Rinse mouth and seek immediate medical attention.
• Spill Management: Carefully collect intact pellets or powder from crushed pellets. Collect in a sealed, labeled container for hazardous waste disposal.
• Storage: Store pellets in the original tightly sealed container at room temperature (20–25°C) in a desiccator, protected from light and moisture.

By purchasing from RChems EU, you confirm that you are a qualified researcher (or authorized agent) and that your facility can handle this compound safely.

Global Shipping & Discreet Delivery

RChems EU has perfected a discreet, reliable global logistics system for all research chemical orders, including 2F-DCK 50 mg pellets. We understand that confidentiality is essential for many academic and private research organizations.

What discreet delivery means for you:

• Plain Outer Packaging: Your order arrives in a non-descript padded envelope or small cardboard box. No logos, no brand names, no chemical identifiers.
• Unmarked Shipping Label: The return address uses a generic name (e.g., “L.C. Distribution” or “WH Logistics”). No reference to “RChems EU” or “2F-DCK.”
• Vacuum-Sealed Inner Bags: Pellet blister packs or vials are heat-sealed to prevent tampering. No chemical name appears on the inner packaging.
• No External Documentation: Invoices, COAs, or packing slips are sent via encrypted email only—never placed inside the parcel.

Fast worldwide delivery times (tracked):

Region	Estimated Transit Time
USA & Canada	5–9 business days
Europe (UK, Germany, France, Spain, Italy, Netherlands)	3–7 business days
Australia & New Zealand	7–12 business days
Rest of World (select countries)	7–14 business days

Every shipment includes a real-time tracking number. Expedited courier options (FedEx Priority, DHL Express) are available at checkout for faster delivery (2–5 days globally).

Why Choose RChems EU?

• Stealth Packaging Experts: Over 7,000 successful shipments to 45+ countries with minimal customs interference.
• Third-Party Verified Purity: Every batch of active ingredient is independently tested. We do not sell unverified material.
• Pre-Dosed Convenience: 50 mg pellets eliminate the need for analytical weighing, saving time and reducing variability.
• Responsive Scientific Support: Technical inquiries answered within 24 hours. Replacement policy for lost or damaged shipments (terms apply).
• Flexible Payment Methods: Secure cryptocurrency (BTC, ETH, USDT) and select credit card options.
• Global Compliance Awareness: We monitor international regulations and adjust shipping policies accordingly.

Legal & Safety Disclaimer

⚠️ IMPORTANT – READ CAREFULLY BEFORE PURCHASING

2F-DCK 50 mg pellets are sold by RChems EU strictly as a research chemical and are not for human consumption, animal testing, or any form of in vivo use without appropriate institutional ethical approval. This product is not a pharmaceutical, medicinal product, dietary supplement, or recreational substance.

Legal Status Varies by Jurisdiction: 2F-DCK may be a controlled substance or regulated analog in certain countries, states, or territories. In the United States, ketamine is a Schedule III controlled substance, and structural analogs may be considered controlled substance analogues under the Federal Analogue Act (21 U.S.C. § 813) if intended for human consumption. Several European countries have specific analogue legislation or blanket scheduling for arylcyclohexylamines. It is your sole responsibility to verify the legal status of 2F-DCK in your country, state, or province before ordering.

By completing your purchase, you certify that:

1. You are at least 18 years of age.
2. You are a qualified researcher affiliated with a bona fide laboratory or academic institution.
3. You will use this product exclusively for lawful, laboratory-based research purposes.
4. You will not introduce this compound into the body of any human or animal.

RChems EU reserves the right to cancel any order that appears destined for non-research use or for a jurisdiction where 2F-DCK is prohibited.

FAQ Section

1. What are 2F-DCK 50 mg pellets used for in research?

2F-DCK 50 mg pellets are pre-dosed solid dosage units containing 2-fluorodeschloroketamine, a fluorinated ketamine analog. They are used in neuropharmacological research to study NMDA receptor antagonism, the phencyclidine (PCP) binding site within the NMDA receptor ion channel, and structure-activity relationships comparing halogen substitution (fluorine vs. chlorine). The pre-dosed format is particularly valuable for dose-response studies, reducing measurement variability and saving laboratory time.

2. How do I prepare the pellets for use in assays?

Pellets can be dissolved in an appropriate organic solvent (e.g., ethanol, methanol, or DMSO) to create a stock solution. The exact concentration should be verified by UV spectrophotometry or HPLC before use. The pellet matrix is designed to fully disintegrate and release the active compound in these solvents. For aqueous buffers, first dissolve the pellet in a small volume of ethanol or DMSO, then dilute with buffer (keeping final organic solvent concentration below 1-2% to avoid interference with biological assays).

3. Are the 50 mg pellets homogeneous in content?

Yes. Every pellet in a given batch contains a verified 50 mg (±5%) of 2F-DCK. RChems EU performs random sampling and content uniformity testing on each production batch to ensure consistent dosage across all pellets. The Certificate of Analysis (COA) includes content uniformity data upon request.

4. Is 2F-DCK legal to buy and possess for research?

Legality depends on your jurisdiction. 2F-DCK is not explicitly scheduled at the US federal level but may be considered a controlled substance analogue under the Federal Analogue Act (21 U.S.C. § 813) if intended for human consumption. Many European countries have analogue legislation or specific scheduling for arylcyclohexylamines. You must check your local regulations before ordering. RChems EU ships on the condition that you assume full legal responsibility.

5. How discreet is the shipping from RChems EU?

Extremely discreet. All orders, including 2F-DCK 50 mg pellets, are shipped in plain, unmarked packaging with no external branding. The shipping label uses a generic return address. Inner packaging is vacuum-sealed with no chemical names visible. Our stealth protocol has enabled successful deliveries to over 45 countries with a 99%+ success rate.

6. What is the purity of the 2F-DCK in the pellets?

The active ingredient in every pellet is independently tested to be ≥99% pure via HPLC-DAD, with confirmation by LC-MS and ¹H/¹³C NMR. A lot-specific Certificate of Analysis (COA) for the active ingredient is available for every order upon request.

7. How should I store 2F-DCK 50 mg pellets?

Store pellets in the original tightly sealed container at room temperature (20–25°C) in a desiccator, protected from light and moisture. Avoid exposure to extreme heat or humidity. The pellet formulation offers enhanced stability compared to powdered forms.

8. What is the difference between 2F-DCK pellets and 2F-DCK powder?

The active compound is identical—both contain 2-fluorodeschloroketamine with ≥99% purity. The difference is the form factor: pellets are pre-dosed 50 mg units, while powder requires manual weighing on an analytical balance. Pellets offer convenience, reduced measurement error, and time savings for repetitive experiments, but may require dissolution in organic solvent before use in aqueous assay systems. Powder offers flexibility for custom dosing but requires precise weighing equipment and technique.

9. What is the difference between 2F-DCK and ketamine?

The key structural difference is the halogen substitution:

• Ketamine has a 2-chloro group on the phenyl ring
• 2F-DCK has a 2-fluoro group on the phenyl ring

Both share the same N-methyl group and cyclohexanone ring. In NMDA receptor research, fluorine substitution affects:

• Electronic properties and receptor binding kinetics
• Metabolic stability (fluorine can block oxidative metabolism at adjacent sites)
• Lipophilicity and blood-brain barrier permeability

Comparing these two compounds allows researchers to map the impact of halogen substitution (F vs. Cl) on arylcyclohexylamine pharmacology.

10. Do you offer a reshipment policy if customs seizes my package?

Yes. RChems EU offers a one-time reshipment policy for confirmed customs seizures in most countries, provided that the original shipping address is valid and the buyer did not violate known local laws. Crypto payments qualify for the full reshipment guarantee. Terms and conditions apply—please contact customer support for details.

11. Can I get a Certificate of Analysis (COA) before ordering?

Absolutely. Contact our support team via email with the product name (2F-DCK 50 mg pellets) and your research affiliation. We will provide a redacted or full COA for the active ingredient batch, including HPLC chromatograms and NMR spectra (with characteristic fluorine coupling patterns), subject to verification of legitimate research intent.

Ready to advance your fluorinated arylcyclohexylamine research with pre-dosed convenience? Order 2F-DCK 50 mg pellets from RChems EU today and experience unmatched product quality, stealth global delivery, and professional scientific support. Buy 2F-DCK 50 MG Pellets for Research 

RChems EU – Your trusted global supplier of 99% pure research chemicals.