5-MeO-DALT free base

Buy 5-MeO-DALT Free Base Research Chemical Online – USA, Europe & Worldwide

Among the diverse family of 5-methoxylated tryptamines, 5-MeO-DALT free base (5-methoxy-N,N-diallyltryptamine) occupies a distinctive position due to its unique diallyl substitution pattern. Unlike the more common methyl, ethyl, or isopropyl groups found on the terminal amine of other tryptamines, 5-MeO-DALT features two allyl groups (CH₂=CH-CH₂-), each containing a terminal carbon-carbon double bond. This structural feature not only influences the compound’s receptor binding properties but also offers potential for subsequent chemical derivatization or conjugation studies.

The free base form is the non-ionized, lipophilicz version of the molecule, which differs from salt forms in solubility and physical properties. This form is particularly valuable for research applications requiring solubility in non-polar organic solvents or for studies examining membrane permeability and passive diffusion. For researchers investigating structure-activity relationships within the tryptamine family, 5-MeO-DALT free base offers a unique tool for understanding how unsaturated N-alkyl substituents (allyl groups vs. saturated propyl groups) impact serotonin receptor selectivity, intrinsic activity, and metabolic stability. When you buy 5-MeO-DALT free base from RChems EU, you acquire a high-purity research compound manufactured under strict quality controls. Our 99% pure 5-MeO-DALT free base is intended exclusively for laboratory research—not for human or animal consumption—enabling precise, reproducible experiments in receptor pharmacology, neurochemistry, and structure-activity relationship (SAR) studies.

Key Features & Benefits

• Verified 99%+ Purity: Every batch undergoes independent HPLC, LC-MS, and ¹H/¹³C NMR analysis to guarantee ≥99% purity.
• Unique Diallyl N-Substitution: Two allyl groups containing terminal alkenes enable SAR studies comparing unsaturated vs. saturated N-alkyl chains (e.g., 5-MeO-DALT vs. 5-MeO-DPT).
• 5-Methoxy Substitution: The methoxy group at the 5-position enhances metabolic stability and modulates receptor binding affinity compared to non-methoxylated tryptamines.
• Free Base Form: Lipophilic, non-ionized form suitable for research requiring solubility in non-polar organic solvents and membrane permeability studies.
• Potential for Derivatization: The terminal alkene groups may serve as handles for further chemical modification in synthetic research applications.
• Worldwide Delivery: Fast, tracked shipping to the USA, Canada, Europe, Australia, and select Asian research hubs.
• Discreet Packaging Protocol: Plain outer boxes, unmarked labels, vacuum-sealed inner bags—no chemical names on the parcel.

Product Specifications

Applications & Usage

⚠️ Strictly for laboratory research use only. Not for human or animal consumption.

5-MeO-DALT free base is utilized in a range of non-clinical, pre-clinical, and basic science research applications. Typical areas of investigation include:

• Serotonin Receptor Binding Assays: Evaluating affinity (Ki) for 5-HT1A, 5-HT2A, 5-HT2C, and other serotonin receptor subtypes using radioligand displacement (e.g., [³H]8-OH-DPAT for 5-HT1A, [³H]ketanserin for 5-HT2A, [³H]mesulergine for 5-HT2C).
• G-protein Activation Functional Studies: Measuring [³⁵S]GTPγS binding or BRET-based biosensors to assess efficacy and potency at serotonin receptors in transfected cell lines (e.g., HEK-293 cells expressing human 5-HT2A receptors).
• Structure-Activity Relationship (SAR) Investigations: Systematically comparing 5-MeO-DALT with 5-MeO-DMT (dimethyl), 5-MeO-DET (diethyl), 5-MeO-DPT (dipropyl), and 5-MeO-DiPT (diisopropyl) to map the impact of N-alkyl chain saturation, length, and branching on receptor selectivity, intrinsic activity, and metabolic stability. The diallyl substitution in 5-MeO-DALT provides a critical comparison point for unsaturated vs. saturated three-carbon chains.
• Metabolic Stability Research: Evaluating phase I metabolism using hepatic microsomes or S9 fractions with LC-MS/MS quantification, particularly O-demethylation, N-dealkylation, and epoxidation of the terminal alkenes.
• Chemical Derivatization Studies: Utilizing the terminal alkene groups for subsequent chemical modifications (e.g., hydrogenation, epoxidation, cross-coupling) in synthetic research applications.
• Analytical Reference Standard: Serving as a high-purity calibrant for forensic toxicology, wastewater analysis, or novel psychoactive substance (NPS) screening methods.
• In Vitro Neurotoxicity Screening: Assessing cytotoxicity and oxidative stress markers in neuronal cell cultures (e.g., SH-SY5Y, primary cortical neurons).

Researchers are encouraged to consult peer-reviewed literature (e.g., Journal of Medicinal Chemistry, Neuropharmacology, ACS Chemical Neuroscience, Psychopharmacology) for established in vitro protocols. RChems EU does not provide research protocols but guarantees the compound’s structural integrity and purity for such applications.

Purity & Testing

Reproducibility in serotonin receptor and neuropharmacology research depends critically on compound purity. Impurities—particularly other 5-methoxylated tryptamine isomers, N-desalkyl byproducts, or synthetic intermediates—can produce false-positive signals in radioligand binding assays or confound functional response curves. That is why 99% pure 5-MeO-DALT free base from RChems EU is subjected to a multi-laboratory quality control workflow:

1. High-Performance Liquid Chromatography (HPLC-DAD): Quantitative analysis at 220 nm, 254 nm, and 280 nm (indole ring absorption). Minimum acceptance criterion: ≥99.0% peak area purity.
2. Liquid Chromatography-Mass Spectrometry (LC-MS): Confirms molecular ion [M+H]⁺ = 271.2 and detects trace-level organic impurities down to 0.05%.
3. Nuclear Magnetic Resonance (NMR): Both proton (¹H) and carbon-13 (¹³C) NMR verify the correct indole ring system, 5-methoxy substitution (characteristic methoxy singlet around 3.8–3.9 ppm), and diallyl N-substitution pattern (characteristic terminal alkene protons around 5.0–5.2 ppm and methine protons around 5.7–5.9 ppm). Any spectral deviation triggers batch rejection.
4. Residual Solvent Analysis (GC-MS): Ensures compliance with ICH limits for Class 2 and Class 3 solvents.
5. Heavy Metal Testing (ICP-MS): Confirms levels below 20 ppm for lead, arsenic, cadmium, and mercury.

Each batch is assigned a unique lot number, and a Certificate of Analysis (COA) is available upon request. This rigorous testing ensures that when you buy 5-MeO-DALT free base for research, you receive a compound that performs consistently from order to order.

Safety & Handling Guidelines

⚠️ FOR LABORATORY RESEARCH USE ONLY. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

• Personal Protective Equipment (PPE): Always wear nitrile gloves, a lab coat, and chemical splash goggles when handling 5-MeO-DALT free base.
• Engineering Controls: Use a certified chemical fume hood or glove box to prevent inhalation of airborne particulates.
• First Aid Measures:
  • Inhalation: Remove to fresh air. If breathing difficulty persists, seek medical attention.
  • Skin Contact: Wash with soap and copious water for 15 minutes. Remove contaminated clothing.
  • Eye Contact: Rinse cautiously with water for 15 minutes. Consult an ophthalmologist if irritation persists.
  • Ingestion: Do NOT induce vomiting. Rinse mouth and seek immediate medical attention.
• Spill Management: Vacuum or sweep gently (avoid generating dust). Collect in a sealed, labeled container for hazardous waste disposal.
• Storage: Store in a tightly sealed, amber glass vial at room temperature (20–25°C) in a desiccator or under refrigeration (4°C) for long-term storage. Allow to equilibrate to room temperature before opening to prevent condensation. Note that the free base form may have different physical consistency (waxy) compared to salt forms.

By purchasing from RChems EU, you confirm that you are a qualified researcher (or authorized agent) and that your facility can handle this compound safely.

Global Shipping & Discreet Delivery

RChems EU has perfected a discreet, reliable global logistics system for all research chemical orders, including 5-MeO-DALT free base. We understand that confidentiality is essential for many academic and private research organizations.

What discreet delivery means for you:

• Plain Outer Packaging: Your order arrives in a non-descript padded envelope or small cardboard box. No logos, no brand names, no chemical identifiers.
• Unmarked Shipping Label: The return address uses a generic name (e.g., “L.C. Distribution” or “WH Logistics”). No reference to “RChems EU” or “5-MeO-DALT free base.”
• Vacuum-Sealed Inner Bags: Each bag is heat-sealed to prevent leakage, odor, and tampering. No chemical name appears on the inner bag.
• No External Documentation: Invoices, COAs, or packing slips are sent via encrypted email only—never placed inside the parcel.

Fast worldwide delivery times (tracked):

Every shipment includes a real-time tracking number. Expedited courier options (FedEx Priority, DHL Express) are available at checkout for faster delivery (2–5 days globally).

Why Choose RChems EU?

• Stealth Packaging Experts: Over 7,000 successful shipments to 45+ countries with minimal customs interference.
• Third-Party Verified Purity: Every batch is independently tested. We do not sell unverified or “research grade” material without documentation.
• Responsive Scientific Support: Technical inquiries answered within 24 hours. Replacement policy for lost or damaged shipments (terms apply).
• No Minimum Order Quantity (MOQ): Order 0.25 grams or 5 grams—same meticulous packaging and quality standards.
• Flexible Payment Methods: Secure cryptocurrency (BTC, ETH, USDT) and select credit card options.
• Global Compliance Awareness: We monitor international regulations and adjust shipping policies accordingly.

Legal & Safety Disclaimer

⚠️ IMPORTANT – READ CAREFULLY BEFORE PURCHASING

5-MeO-DALT free base (5-methoxy-N,N-diallyltryptamine) is sold by RChems EU strictly as a research chemical and is not for human consumption, animal testing, or any form of in vivo use without appropriate institutional ethical approval. This product is not a pharmaceutical, medicinal product, dietary supplement, or recreational substance.

Legal Status Varies by Jurisdiction: 5-MeO-DALT free base may be a controlled substance or regulated analog in certain countries, states, or territories. In the United States, it may be considered a controlled substance analogue under the Federal Analogue Act (21 U.S.C. § 813) if intended for human consumption. Several European countries (including Germany, Sweden, and the UK) have specific analogue legislation or blanket scheduling for tryptamine derivatives. It is your sole responsibility to verify the legal status of 5-MeO-DALT free base in your country, state, or province before ordering.

By completing your purchase, you certify that:

1. You are at least 18 years of age.
2. You are a qualified researcher affiliated with a bona fide laboratory or academic institution.
3. You will use this product exclusively for lawful, laboratory-based research purposes.
4. You will not introduce this compound into the body of any human or animal.

RChems EU reserves the right to cancel any order that appears destined for non-research use or for a jurisdiction where 5-MeO-DALT free base is prohibited.

FAQ Section

1. What is 5-MeO-DALT free base used for in research?

5-MeO-DALT free base (5-methoxy-N,N-diallyltryptamine) is used in neuropharmacological research to study serotonin receptor binding affinity (5-HT1A, 5-HT2A, 5-HT2C), the effects of unsaturated N-allyl substitution on tryptamine pharmacology, and structure-activity relationships comparing unsaturated vs. saturated N-alkyl chains. The terminal alkene groups also offer opportunities for chemical derivatization studies.

2. Is 5-MeO-DALT free base legal to buy and possess for research?

Legality depends on your jurisdiction. 5-MeO-DALT is not explicitly scheduled at the US federal level but may be considered a controlled substance analogue under the Federal Analogue Act (21 U.S.C. § 813) if intended for human consumption. Many European countries have analogue legislation or specific tryptamine scheduling. You must check your local regulations before ordering. RChems EU ships on the condition that you assume full legal responsibility.

3. How discreet is the shipping from RChems EU?

Extremely discreet. All 5-MeO-DALT free base orders are shipped in plain, unmarked packaging with no external branding. The shipping label uses a generic return address. Inner bags are vacuum-sealed with no chemical names or CAS numbers visible. Our stealth protocol has enabled successful deliveries to over 45 countries with a 99%+ success rate.

4. What is the guaranteed purity level of your 5-MeO-DALT free base?

Every batch of 5-MeO-DALT free base from RChems EU is independently tested to be ≥99% pure via HPLC-DAD, with confirmation by LC-MS and ¹H/¹³C NMR. A lot-specific Certificate of Analysis (COA) is available for every order upon request.

5. How is the 99% purity tested?

We employ a five-tier analytical protocol:

• HPLC-DAD for quantitative purity (≥99% peak area at 220 nm, 254 nm, and 280 nm).
• LC-MS for molecular weight confirmation ([M+H]⁺ = 271.2) and trace impurity detection down to 0.05%.
• ¹H and ¹³C NMR for structural confirmation (indole ring system, 5-methoxy substitution, diallyl substitution pattern with terminal alkene protons).
• GC-MS for residual solvent analysis (ICH compliance).
• Heavy metal testing (ICP-MS) to confirm levels below 20 ppm.

All testing is performed by an ISO 17025-accredited contract laboratory.

6. Can you ship 5-MeO-DALT free base to my country (USA, UK, Germany, Australia, Canada)?

RChems EU ships 5-MeO-DALT free base worldwide, including the USA, Canada, United Kingdom, Germany, France, Italy, Spain, Netherlands, Switzerland, Norway, Australia, and New Zealand. However, due to varying legal statuses of tryptamine derivatives, we strongly recommend contacting our support team before ordering if you are located in Germany, Sweden, Finland, or any country with broad analogue legislation. For countries with strict import controls (e.g., Japan, Singapore, South Korea), we do not currently ship 5-MeO-DALT free base.

7. How should I store 5-MeO-DALT free base after delivery?

Store 5-MeO-DALT free base in a tightly sealed, amber glass vial away from light, heat, and moisture. For short-term use (≤3 months), room temperature (20–25°C) in a desiccator is acceptable. For long-term storage (>3 months), refrigerate at 4°C. Always allow the sealed container to reach room temperature before opening to prevent condensation. Note that the free base form may have a waxy or oily consistency compared to salt forms.

8. What makes 5-MeO-DALT different from other 5-methoxylated tryptamines?

The key structural difference lies in the N-alkyl substitution pattern. 5-MeO-DALT features two allyl groups (CH₂=CH-CH₂-), each containing a terminal carbon-carbon double bond. Most other 5-methoxylated tryptamines have saturated alkyl groups (methyl, ethyl, propyl, isopropyl). In serotonin receptor research, comparing 5-MeO-DALT with 5-MeO-DPT (dipropyl, saturated analog) allows researchers to investigate how unsaturation in the N-alkyl chain influences receptor binding selectivity, intrinsic activity, and metabolic stability.

9. What is the difference between 5-MeO-DALT free base and a salt form?

The free base is the non-ionized, lipophilic form of the molecule. It is generally soluble in non-polar organic solvents (ethanol, DMSO) and has limited water solubility. The free base may have a waxy or oily consistency. In contrast, a salt form (e.g., hydrochloride or fumarate) is ionized, water-soluble, and typically a crystalline solid. The choice between forms depends on the specific research application: free base is preferred for studies requiring non-polar solvents or membrane permeability, while salts are preferred for aqueous buffer systems.

10. Do you offer a reshipment policy if customs seizes my package?

Yes. RChems EU offers a one-time reshipment policy for confirmed customs seizures in most countries, provided that the original shipping address is valid and the buyer did not violate known local laws. Crypto payments qualify for the full reshipment guarantee. Terms and conditions apply—please contact customer support for details.

11. Can I get a Certificate of Analysis (COA) before ordering?

Absolutely. Contact our support team via email with the product name (5-MeO-DALT free base or 5-methoxy-N,N-diallyltryptamine) and your research affiliation. We will provide a redacted or full COA for the current batch, including HPLC chromatograms and NMR spectra, subject to verification of legitimate research intent.

Ready to advance your serotonin receptor and diallyltryptamine research? Order high-purity 5-MeO-DALT free base from RChems EU today and experience unmatched product quality, stealth global delivery, and professional scientific support. Buy 5-MeO-DALT Free Base for Research

RChems EU – Your trusted global supplier of 99% pure research chemicals.