Buy 5-MeO-DiPT Hydrochloride Research Chemical Online – USA, Europe & Worldwide
Among the diverse family of 5-methoxylated tryptamines, 5-MeO-DiPT hydrochloride (5-methoxy-N,N-diisopropyltryptamine HCl) occupies a distinctive position due to its unique structural features and corresponding pharmacological profile. Often referred to in the scientific literature by its colloquial designation “Foxy,” this compound combines a methoxy group at the 5-position of the indole ring with two bulky isopropyl groups on the terminal amine nitrogen. This combination of a 5-methoxy substituent and diisopropyl substitution creates a molecule with distinct steric and electronic properties that differentiate it from other tryptamines such as 5-MeO-DMT (dimethyl) or 5-MeO-DET (diethyl).
The bulky isopropyl groups restrict conformational flexibility and alter receptor binding kinetics, while the 5-methoxy group enhances metabolic stability and modulates receptor affinity. For researchers investigating structure-activity relationships within the tryptamine family, 5-MeO-DiPT HCl offers a valuable tool for understanding how increasing N-alkyl chain length and branching impacts serotonin receptor selectivity, intrinsic activity, and pharmacokinetic properties. When you buy 5-MeO-DiPT hydrochloride from RChems EU, you acquire a high-purity research compound manufactured under strict quality controls. Our 99% pure 5-MeO-DiPT HCl is intended exclusively for laboratory research—not for human or animal consumption—enabling precise, reproducible experiments in receptor pharmacology, neurochemistry, and behavioral neuroscience.
Key Features & Benefits
- Verified 99%+ Purity: Every batch undergoes independent HPLC, LC-MS, and ¹H/¹³C NMR analysis to guarantee ≥99% purity.
- Bulky Diisopropyl N-Substitution: The two isopropyl groups create significant steric bulk, enabling SAR studies on the impact of branched alkyl chains on receptor binding and activation.
- 5-Methoxy Substitution: The methoxy group at the 5-position modulates metabolic stability and receptor binding affinity compared to non-methoxylated tryptamines.
- Hydrochloride Salt Form: Excellent water solubility and crystalline stability for precise solution preparation in assay buffers.
- Distinct Pharmacological Profile: Offers unique research opportunities compared to other 5-methoxylated tryptamines.
- Worldwide Delivery: Fast, tracked shipping to the USA, Canada, Europe, Australia, and select Asian research hubs.
- Discreet Packaging Protocol: Plain outer boxes, unmarked labels, vacuum-sealed inner bags—no chemical names on the parcel.
Product Specifications
| Property | Specification |
|---|---|
| IUPAC Name | 2-(5-methoxy-1H-indol-3-yl)-N,N-diisopropylethan-1-amine hydrochloride |
| CAS Number | Not publicly assigned (research chemical) |
| Synonyms | 5-Methoxy-N,N-diisopropyltryptamine HCl, Foxy (research designation), 5-MeO-DiPT HCl |
| Physical State | Crystalline solid |
| Purity Analysis | HPLC (≥99%), LC-MS, ¹H/¹³C NMR |
| Loss on Drying | <0.5% |
| Residual Solvents | Compliant with ICH Q3C guidelines |
| Heavy Metals | <20 ppm |
| Chemical Class | Tryptamine / 5-Methoxytryptamine derivative |
Applications & Usage
⚠️ Strictly for laboratory research use only. Not for human or animal consumption.
5-MeO-DiPT hydrochloride is utilized in a range of non-clinical, pre-clinical, and basic science research applications. Typical areas of investigation include:
- Serotonin Receptor Binding Assays: Evaluating affinity (Ki) for 5-HT1A, 5-HT2A, 5-HT2C, and other serotonin receptor subtypes using radioligand displacement (e.g., [³H]8-OH-DPAT for 5-HT1A, [³H]ketanserin for 5-HT2A, [³H]mesulergine for 5-HT2C).
- G-protein Activation Functional Studies: Measuring [³⁵S]GTPγS binding or BRET-based biosensors to assess efficacy and potency at serotonin receptors in transfected cell lines (e.g., HEK-293 cells expressing human 5-HT2A receptors).
- Structure-Activity Relationship (SAR) Investigations: Systematically comparing 5-MeO-DiPT with 5-MeO-DMT (dimethyl), 5-MeO-MET (methylethyl), 5-MeO-DET (diethyl), and 5-MeO-DPT (dipropyl) to map the impact of N-alkyl chain length and branching on receptor selectivity, intrinsic activity, and metabolic stability. The diisopropyl substitution in 5-MeO-DiPT provides a critical data point on the effects of steric bulk.
- Metabolic Stability Research: Evaluating phase I metabolism using hepatic microsomes or S9 fractions with LC-MS/MS quantification, particularly O-demethylation and N-dealkylation pathways. The bulky isopropyl groups may confer resistance to certain metabolic pathways.
- Analytical Reference Standard: Serving as a high-purity calibrant for forensic toxicology, wastewater analysis, or novel psychoactive substance (NPS) screening methods.
- In Vitro Neurotoxicity Screening: Assessing cytotoxicity and oxidative stress markers in neuronal cell cultures (e.g., SH-SY5Y, primary cortical neurons).
Researchers are encouraged to consult peer-reviewed literature (e.g., Journal of Medicinal Chemistry, Neuropharmacology, ACS Chemical Neuroscience, Psychopharmacology) for established in vitro protocols. RChems EU does not provide research protocols but guarantees the compound’s structural integrity and purity for such applications.
Purity & Testing
Reproducibility in serotonin receptor and neuropharmacology research depends critically on compound purity. Impurities—particularly other 5-methoxylated tryptamine isomers, N-desalkyl byproducts, or synthetic intermediates—can produce false-positive signals in radioligand binding assays or confound functional response curves. That is why 99% pure 5-MeO-DiPT hydrochloride from RChems EU is subjected to a multi-laboratory quality control workflow:
- High-Performance Liquid Chromatography (HPLC-DAD): Quantitative analysis at 220 nm, 254 nm, and 280 nm (indole ring absorption). Minimum acceptance criterion: ≥99.0% peak area purity.
- Liquid Chromatography-Mass Spectrometry (LC-MS): Confirms molecular ion [M+H]⁺ = 275.2 for the freebase and detects trace-level organic impurities down to 0.05%.
- Nuclear Magnetic Resonance (NMR): Both proton (¹H) and carbon-13 (¹³C) NMR verify the correct indole ring system, 5-methoxy substitution (characteristic methoxy singlet around 3.8–3.9 ppm), and diisopropyl N-substitution pattern (characteristic isopropyl methine and methyl splitting). Any spectral deviation triggers batch rejection.
- Residual Solvent Analysis (GC-MS): Ensures compliance with ICH limits for Class 2 and Class 3 solvents.
- Heavy Metal Testing (ICP-MS): Confirms levels below 20 ppm for lead, arsenic, cadmium, and mercury.
Each batch is assigned a unique lot number, and a Certificate of Analysis (COA) is available upon request. This rigorous testing ensures that when you buy 5-MeO-DiPT HCl for research, you receive a compound that performs consistently from order to order.
Safety & Handling Guidelines
⚠️ FOR LABORATORY RESEARCH USE ONLY. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
- Personal Protective Equipment (PPE): Always wear nitrile gloves, a lab coat, and chemical splash goggles when handling 5-MeO-DiPT hydrochloride powder.
- Engineering Controls: Use a certified chemical fume hood or glove box to prevent inhalation of airborne particulates.
- First Aid Measures:
- Inhalation: Remove to fresh air. If breathing difficulty persists, seek medical attention.
- Skin Contact: Wash with soap and copious water for 15 minutes. Remove contaminated clothing.
- Eye Contact: Rinse cautiously with water for 15 minutes. Consult an ophthalmologist if irritation persists.
- Ingestion: Do NOT induce vomiting. Rinse mouth and seek immediate medical attention.
- Spill Management: Vacuum or sweep gently (avoid generating dust). Collect in a sealed, labeled container for hazardous waste disposal.
- Storage: Store in a tightly sealed, amber glass vial at room temperature (20–25°C) in a desiccator or under refrigeration (4°C) for long-term storage. Allow to equilibrate to room temperature before opening to prevent condensation.
By purchasing from RChems EU, you confirm that you are a qualified researcher (or authorized agent) and that your facility can handle this compound safely.
Global Shipping & Discreet Delivery
RChems EU has perfected a discreet, reliable global logistics system for all research chemical orders, including 5-MeO-DiPT hydrochloride. We understand that confidentiality is essential for many academic and private research organizations.
What discreet delivery means for you:
- Plain Outer Packaging: Your order arrives in a non-descript padded envelope or small cardboard box. No logos, no brand names, no chemical identifiers.
- Unmarked Shipping Label: The return address uses a generic name (e.g., “L.C. Distribution” or “WH Logistics”). No reference to “RChems EU” or “5-MeO-DiPT hydrochloride.”
- Vacuum-Sealed Inner Bags: Each bag is heat-sealed to prevent leakage, odor, and tampering. No chemical name appears on the inner bag.
- No External Documentation: Invoices, COAs, or packing slips are sent via encrypted email only—never placed inside the parcel.
Fast worldwide delivery times (tracked):
| Region | Estimated Transit Time |
|---|---|
| USA & Canada | 5–9 business days |
| Europe (UK, Germany, France, Spain, Italy, Netherlands) | 3–7 business days |
| Australia & New Zealand | 7–12 business days |
| Rest of World (select countries) | 7–14 business days |
Every shipment includes a real-time tracking number. Expedited courier options (FedEx Priority, DHL Express) are available at checkout for faster delivery (2–5 days globally).
Why Choose RChems EU?
- Stealth Packaging Experts: Over 7,000 successful shipments to 45+ countries with minimal customs interference.
- Third-Party Verified Purity: Every batch is independently tested. We do not sell unverified or “research grade” material without documentation.
- Responsive Scientific Support: Technical inquiries answered within 24 hours. Replacement policy for lost or damaged shipments (terms apply).
- No Minimum Order Quantity (MOQ): Order 0.25 grams or 5 grams—same meticulous packaging and quality standards.
- Flexible Payment Methods: Secure cryptocurrency (BTC, ETH, USDT) and select credit card options.
- Global Compliance Awareness: We monitor international regulations and adjust shipping policies accordingly.
Legal & Safety Disclaimer
⚠️ IMPORTANT – READ CAREFULLY BEFORE PURCHASING
5-MeO-DiPT hydrochloride (5-methoxy-N,N-diisopropyltryptamine HCl) is sold by RChems EU strictly as a research chemical and is not for human consumption, animal testing, or any form of in vivo use without appropriate institutional ethical approval. This product is not a pharmaceutical, medicinal product, dietary supplement, or recreational substance.
Legal Status Varies by Jurisdiction: 5-MeO-DiPT hydrochloride may be a controlled substance or regulated analog in certain countries, states, or territories. In the United States, it may be considered a controlled substance analogue under the Federal Analogue Act (21 U.S.C. § 813) if intended for human consumption. Several European countries (including Germany, Sweden, and the UK) have specific analogue legislation or blanket scheduling for tryptamine derivatives. It is your sole responsibility to verify the legal status of 5-MeO-DiPT hydrochloride in your country, state, or province before ordering.
By completing your purchase, you certify that:
- You are at least 18 years of age.
- You are a qualified researcher affiliated with a bona fide laboratory or academic institution.
- You will use this product exclusively for lawful, laboratory-based research purposes.
- You will not introduce this compound into the body of any human or animal.
RChems EU reserves the right to cancel any order that appears destined for non-research use or for a jurisdiction where 5-MeO-DiPT hydrochloride is prohibited.
FAQ Section
1. What is 5-MeO-DiPT hydrochloride used for in research?
5-MeO-DiPT hydrochloride (5-methoxy-N,N-diisopropyltryptamine HCl) is used in neuropharmacological research to study serotonin receptor binding affinity (particularly 5-HT2A and 5-HT1A), the effects of bulky N-alkyl substitution on tryptamine pharmacology, and structure-activity relationships among 5-methoxylated tryptamines. The diisopropyl substitution provides a unique steric profile for SAR studies comparing different N-alkyl chain lengths and branching patterns.
2. Is 5-MeO-DiPT hydrochloride legal to buy and possess for research?
Legality depends on your jurisdiction. 5-MeO-DiPT is not explicitly scheduled at the US federal level but may be considered a controlled substance analogue under the Federal Analogue Act (21 U.S.C. § 813) if intended for human consumption. Many European countries have analogue legislation or specific tryptamine scheduling. You must check your local regulations before ordering. RChems EU ships on the condition that you assume full legal responsibility.
3. How discreet is the shipping from RChems EU?
Extremely discreet. All 5-MeO-DiPT hydrochloride orders are shipped in plain, unmarked packaging with no external branding. The shipping label uses a generic return address. Inner bags are vacuum-sealed with no chemical names or CAS numbers visible. Our stealth protocol has enabled successful deliveries to over 45 countries with a 99%+ success rate.
4. What is the guaranteed purity level of your 5-MeO-DiPT hydrochloride?
Every batch of 5-MeO-DiPT hydrochloride from RChems EU is independently tested to be ≥99% pure via HPLC-DAD, with confirmation by LC-MS and ¹H/¹³C NMR. A lot-specific Certificate of Analysis (COA) is available for every order upon request.
5. How is the 99% purity tested?
We employ a five-tier analytical protocol:
- HPLC-DAD for quantitative purity (≥99% peak area at 220 nm, 254 nm, and 280 nm).
- LC-MS for molecular weight confirmation ([M+H]⁺ = 275.2 for freebase) and trace impurity detection down to 0.05%.
- ¹H and ¹³C NMR for structural confirmation (indole ring system, 5-methoxy substitution, diisopropyl N-substitution pattern).
- GC-MS for residual solvent analysis (ICH compliance).
- Heavy metal testing (ICP-MS) to confirm levels below 20 ppm.
All testing is performed by an ISO 17025-accredited contract laboratory.
6. Can you ship 5-MeO-DiPT hydrochloride to my country (USA, UK, Germany, Australia, Canada)?
RChems EU ships 5-MeO-DiPT hydrochloride worldwide, including the USA, Canada, United Kingdom, Germany, France, Italy, Spain, Netherlands, Switzerland, Norway, Australia, and New Zealand. However, due to varying legal statuses of tryptamine derivatives, we strongly recommend contacting our support team before ordering if you are located in Germany, Sweden, Finland, or any country with broad analogue legislation. For countries with strict import controls (e.g., Japan, Singapore, South Korea), we do not currently ship 5-MeO-DiPT hydrochloride.
7. How should I store 5-MeO-DiPT hydrochloride after delivery?
Store 5-MeO-DiPT hydrochloride in a tightly sealed, amber glass vial away from light, heat, and moisture. For short-term use (≤3 months), room temperature (20–25°C) in a desiccator is acceptable. For long-term storage (>3 months), refrigerate at 4°C. Always allow the sealed container to reach room temperature before opening to prevent condensation-induced degradation.
8. What makes 5-MeO-DiPT different from 5-MeO-DMT or 5-MeO-DET?
The key structural differences lie in the N-alkyl substitution pattern:
- 5-MeO-DMT has two methyl groups (N,N-dimethyl) – small, linear
- 5-MeO-DET has two ethyl groups (N,N-diethyl) – medium, linear
- 5-MeO-DiPT has two isopropyl groups (N,N-diisopropyl) – bulky, branched
In serotonin receptor research, the bulky, branched isopropyl groups restrict conformational flexibility and alter receptor binding kinetics. This structural feature distinguishes 5-MeO-DiPT from its linear-chain analogs and makes it a valuable tool for understanding how steric bulk at the terminal amine influences receptor selectivity and intrinsic activity.
9. Why is 5-MeO-DiPT sometimes referred to as “Foxy” in research literature?
“Foxy” is a colloquial research designation that has appeared in some scientific and forensic literature as a shorthand reference for 5-MeO-DiPT. Researchers should be aware of this alternative designation when conducting literature searches or reviewing forensic case reports, though RChems EU uses only the standard chemical nomenclature (5-MeO-DiPT hydrochloride or 5-methoxy-N,N-diisopropyltryptamine HCl) for all product labeling and documentation.
10. Do you offer a reshipment policy if customs seizes my package?
Yes. RChems EU offers a one-time reshipment policy for confirmed customs seizures in most countries, provided that the original shipping address is valid and the buyer did not violate known local laws. Crypto payments qualify for the full reshipment guarantee. Terms and conditions apply—please contact customer support for details.
11. Can I get a Certificate of Analysis (COA) before ordering?
Absolutely. Contact our support team via email with the product name (5-MeO-DiPT hydrochloride or 5-methoxy-N,N-diisopropyltryptamine HCl) and your research affiliation. We will provide a redacted or full COA for the current batch, including HPLC chromatograms and NMR spectra, subject to verification of legitimate research intent.
Ready to advance your serotonin receptor and branched-chain tryptamine research? Order high-purity 5-MeO-DiPT hydrochloride from RChems EU today and experience unmatched product quality, stealth global delivery, and professional scientific support. Buy 5-MeO-DiPT Hydrochloride for Research.
RChems EU – Your trusted global supplier of 99% pure research chemicals.



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