AL-LAD L-tartrate Pure

Buy AL-LAD L-tartrate Pure Research Chemical Online – USA, Europe & Worldwide

RChems EU is proud to offer AL-LAD L-tartrate Pure, a high-purity research chemical designed for advanced neuropharmacological and structure-activity relationship (SAR) studies. AL-LAD (6-Allyl-6-nor-lysergic acid diethylamide) is a renowned lysergamide analogue distinguished by the substitution of the methyl group at the indole nitrogen (N6 position) with an allyl group (-CH₂-CH=CH₂). This seemingly minor structural change relative to LSD (which bears an N6-methyl) produces significant differences in receptor binding kinetics, functional selectivity, and metabolic stability. Our AL-LAD L-tartrate Pure is supplied as a crystalline, non-hygroscopic salt, ensuring accurate gravimetric dosing and long-term stability for reproducible research outcomes. Whether you need to buy AL-LAD L-tartrate for serotonin 5-HT2A receptor binding assays, comparative pharmacology with LSD and other lysergamides, or metabolic profiling studies, RChems EU delivers uncompromising quality. As a trusted global supplier, we ensure every order arrives via fast worldwide delivery in discreet, unmarked packaging with no external chemical identifiers.

Key Features & Benefits

• 99% Purity Guaranteed: Validated by HPLC-DAD, ¹H/¹³C NMR, and HRMS—no adulterants, no cutting agents.
• Unique Allyl Substitution: The N6-allyl group provides distinct steric and electronic properties for advanced SAR research compared to N6-methyl (LSD) or N6-ethyl (ETH-LAD) analogues.
• L-tartrate Salt Form: Superior aqueous solubility (>5 mg/mL) and improved thermal stability compared to freebase.
• Research-Ready Crystalline Powder: Non-hygroscopic, static-free, and easy to handle for precise microbalance weighing.
• Discreet Global Shipping: Plain outer packaging, vacuum-sealed inner pouch, no chemical names on parcel.
• Batch Traceability: Every shipment includes a Certificate of Analysis (COA) linked to a unique lot number.

Product Specifications

Applications & Usage

AL-LAD L-tartrate Pure is intended exclusively for legitimate scientific research. Typical applications include:

• Receptor Binding Affinity Studies: Quantifying AL-LAD’s binding affinity (Ki) at human serotonin receptors (5-HT2A, 5-HT2B, 5-HT2C, 5-HT1A, 5-HT7) using radioligand displacement assays (e.g., [³H]-LSD, [³H]-ketanserin, [³H]-8-OH-DPAT). Compare against LSD, ETH-LAD, and PRO-LAD to understand the impact of N6 alkyl chain length and unsaturation.
• Functional GPCR Assays: Measuring Gαq-mediated IP3 accumulation, calcium flux (using fluorescent indicators such as Fluo-4), or β-arrestin recruitment in transfected cell lines (HEK-293 or CHO-K1 expressing recombinant human 5-HT2A receptors).
• Selectivity Profiling: Determining AL-LAD’s selectivity ratio across the serotonin receptor family and against off-target targets (dopamine D2, adrenergic α2, histamine H1) using broad-panel screening (e.g., Eurofins Cerep, NIMH Psychoactive Drug Screening Program protocols).
• Metabolic Stability Studies: Investigating phase I (CYP450-mediated N-dealkylation and allyl oxidation) using human liver microsomes (HLM), recombinant CYP enzymes (CYP3A4, CYP2D6, CYP1A2), or primary hepatocytes.
• Structure-Activity Relationship (SAR) Research: Systematically comparing the N6-allyl group (AL-LAD) against N6-methyl (LSD), N6-ethyl (ETH-LAD), N6-propyl (PRO-LAD), and N6-cyclopropylmethyl (CYP-LAD) to map steric and electronic tolerances at the receptor binding pocket.
• Analytical Reference Standard: Use as a certified reference material for LC-MS/MS or LC-QTOF method development in forensic toxicology and clinical research for the detection of emerging lysergamides.
• In Vitro Neuroplasticity Studies: Investigating the effects of AL-LAD on neuritogenesis, dendritic arborization, and TrkB signaling in primary cortical neuron cultures (subject to appropriate ethical approvals).

When researchers buy AL-LAD for research, the L-tartrate salt form is particularly advantageous because it dissolves directly in phosphate-buffered saline (PBS), HEPES buffer, or standard cell culture media (DMEM, RPMI, Neurobasal) without requiring DMSO or ethanol co-solvents that can confound cellular assays or induce cytotoxicity at higher concentrations. This ensures reproducible, publication-grade results across multiple experimental replicates and laboratory settings.

Purity & Testing

At RChems EU, rigorous analytical characterization is the foundation of our quality assurance. Every batch of AL-LAD L-tartrate Pure undergoes comprehensive, multi-modal testing before release:

1. High-Performance Liquid Chromatography with Diode Array Detection (HPLC-DAD):
   • Quantifies purity at ≥99% across three UV wavelengths (220 nm, 254 nm, 310 nm) to capture all potential chromophoric impurities.
   • Detects related substances including iso-AL-LAD, lysergic acid, N6-desalkyl degradation products, and unreacted intermediates—each below 0.5% if present.
   • Retention time matched against an in-house primary reference standard.
2. Nuclear Magnetic Resonance Spectroscopy (¹H NMR and ¹³C NMR, 400 MHz or higher):
   • Confirms the expected proton and carbon environments for both the AL-LAD cation and the L-tartrate counterion.
   • Validates the 1:0.5 stoichiometry (two AL-LAD molecules per one tartrate dianion) by integration of characteristic proton signals.
   • Rules out residual solvents (ethyl acetate, dichloromethane, methanol, hexane) above ICH Q3C limits.
   • Confirms the integrity of the allyl group (characteristic vinyl proton signals at δ 5.1–5.9 ppm).
3. High-Resolution Mass Spectrometry (HRMS-ESI or HRMS-TOF):
   • Confirms the exact mass of the [M+H]⁺ ion for the freebase at m/z 380.2333 (calculated for C₂₂H₂₆N₃O).
   • Detects trace impurities with mass accuracy <3 ppm.
   • Confirms the absence of oxidation products (e.g., epoxides on the allyl group).
4. Karl Fischer Coulometric Titration: Ensures residual water content <1.0%, confirming the non-hygroscopic nature of the crystalline salt and ensuring accurate gravimetric dosing.
5. Residual Solvent Analysis (GC-FID with Headspace): Screens for Class 2 and Class 3 solvents per ICH guidelines—all below permitted daily exposure limits for reference standards.
6. Heavy Metals Screening (ICP-MS): Certifies that lead (Pb), arsenic (As), cadmium (Cd), mercury (Hg), and nickel (Ni) are below detectable limits (<1 ppm each).
7. Optical Rotation (Polarimetry): Confirms the expected optical rotation ([α]²⁰D) for the natural ergoline stereochemistry, ruling out racemization or epimerization during synthesis.

When you buy 99% pure AL-LAD L-tartrate from RChems EU, you receive a Certificate of Analysis summarizing all seven tests. This transparency ensures that your research findings are not compromised by hidden impurities—a critical advantage for high-impact publications, regulatory submissions, and inter-laboratory reproducibility.

Safety & Handling Guidelines

FOR LABORATORY RESEARCH USE ONLY. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

• Personal Protective Equipment (PPE): Always wear nitrile gloves (double-gloving recommended for prolonged handling), a chemical-resistant lab coat, and safety goggles with side shields or a full-face shield.
• Engineering Controls: Handle inside a certified chemical fume hood (Class II or higher) or a glovebox. Do not handle on an open laboratory bench. Use HEPA-filtered vacuum systems for powder transfers.
• Dispensing: Use anti-static spatulas and grounded weighing boats to prevent particle dispersion due to static charge. Work in a low-humidity environment if possible.
• Surface Decontamination: Clean spills immediately with 10% sodium hypochlorite solution (bleach) followed by 70% ethanol. Bleach effectively degrades lysergamides via oxidation. Absorb with inert material (e.g., vermiculite) and dispose as hazardous waste.
• Storage: Store in the original amber glass vial with a PTFE-lined or phenolic screw cap. Keep at 2–8°C (standard laboratory refrigerator). Do not freeze, as freeze-thaw cycles may induce crystal lattice changes. Add a desiccant cartridge (silica gel or molecular sieves) for long-term storage (>6 months). Minimize headspace by using appropriately sized vials. Avoid repeated opening; consider aliquoting into smaller, argon-flushed vials for long-term archival.
• Incompatibilities: Avoid strong oxidizing agents (peroxides, permanganates), strong acids (pH <2), direct sunlight, UV light, and temperatures above 40°C. The allyl group may be susceptible to oxidation; store under inert atmosphere (argon or nitrogen) for extended periods.
• Disposal: Follow institutional, local, state, and national hazardous waste regulations for controlled substance analogues and ergoline derivatives. Do not dispose in sink drains or general trash.

Global Shipping & Discreet Delivery

RChems EU recognizes that confidentiality, reliability, and speed are equally critical for research institutions, contract research organizations, and independent investigators worldwide. Every order of AL-LAD L-tartrate Pure is shipped using our advanced StealthShield™ Pro protocol:

• Plain Outer Packaging: No company logos, no branding elements, no product imagery, and no mention of “RChems EU” on the exterior. Return address uses a generic, non-descript logistics partner name (e.g., “LC Distribution Services” or “Global Fulfillment Center”).
• Unmarked Labels: Customs declarations and shipping labels never mention “AL-LAD,” “lysergamide,” “research chemical,” “LSD analogue,” or any related chemical name. Instead, generic, non-alarming descriptions are used exclusively, such as “Laboratory reagent sample for analysis,” “Inert crystalline solid for R&D purposes,” “Chemical reference standard,” or “Non-hazardous research sample.” Quantities are declared accurately but generically.
• Vacuum-Sealed Inner Pouch: The product vial (amber glass with secure cap) is heat-sealed inside a thick, opaque, multi-layer foil vacuum pouch (aluminum-polyethylene laminate). This provides four critical functions: (1) prevents moisture ingress, (2) eliminates any odor transmission (lysergamides are odorless, but precaution is maintained), (3) provides visible tamper evidence, and (4) partially obscures X-ray identification of vial contents.
• Secondary Protection: The vacuum pouch is placed inside a crush-resistant corrugated cardboard box or padded poly mailer with additional bubble wrap or foam inserts for mechanical protection.
• Fast Worldwide Delivery (Typical transit times from dispatch):
  • USA (contiguous): 4–7 business days
  • Canada: 5–8 business days
  • United Kingdom: 4–6 business days
  • European Union (Germany, France, Spain, Italy, Netherlands, Belgium, Austria, etc.): 4–8 business days
  • Switzerland & Norway: 6–9 business days
  • Australia & New Zealand: 6–11 business days
  • Japan, South Korea, Singapore: 6–10 business days
  • Rest of World (South America, South Africa, Middle East excluding restricted regions): 7–14 business days
• Discrete Tracking: A trackable shipping number is provided via encrypted email (ProtonMail-compatible) within 24–48 hours of dispatch. The tracking portal displays only “Shipment in transit,” estimated delivery dates, and origin/destination scans—no product details, no chemical names, no reference to RChems EU or “research chemical.” For European shipments, tracking may be via local postal carriers (Deutsche Post, La Poste, PostNL, Royal Mail) or private couriers (DHL, UPS) depending on destination.

Whether you require AL-LAD L-tartrate discreet shipping to a university neuroscience laboratory, a contract research organization (CRO), a pharmaceutical R&D facility, or a private forensic laboratory, RChems EU guarantees complete confidentiality from checkout through to final delivery.

Why Choose RChems EU?

• Trusted Global Supplier: Thousands of successful shipments to more than 55 countries with a verified 99.5% delivery success rate over 5+ years of operation.
• Stealth Packaging Pioneer: We have continuously refined our discretion methods since 2018, specifically engineered for sensitive research chemicals. Our protocols are regularly updated to adapt to changing international shipping regulations.
• Fast Logistics Network: Pre-cleared routing through EU (Netherlands, Germany) and US (East Coast, West Coast) transshipment hubs significantly reduces customs inspection holds. We monitor global postal disruptions in real-time.
• Responsive Scientific Support: Encrypted email (including ProtonMail and Tutanota) and live chat support available Monday through Saturday (09:00–18:00 GMT+2). Our support team includes chemistry-trained staff who can answer technical questions about handling, solubility, and storage—without making medical or human consumption claims.
• Full Batch Traceability: Every product vial is linked to a unique lot number with a downloadable, fully detailed Certificate of Analysis (COA) containing all seven analytical test results.
• No Minimum Order Quantity: Single vials (250 mg, 500 mg, 1 g, and research-scale quantities) available for independent investigators, graduate students, and academic laboratories with appropriate approvals.
• Secure Payment Options: Multiple encrypted payment methods accepted, including cryptocurrency (Bitcoin, Monero for privacy-focused customers) and secure credit card processing.
• Discrete Billing: Credit card statements show a neutral, non-descript billing descriptor (not “RChems EU” or any chemical-related term).

Legal & Safety Disclaimer

By purchasing AL-LAD L-tartrate Pure from RChems EU, you explicitly acknowledge, agree, and certify to the following:

• Research Use Only: The product is intended strictly for in vitro research, forensic analysis, legitimate scientific investigation, and laboratory use only. It is not for human consumption, veterinary use, in vivo self-administration, or any form of recreational, therapeutic, or medical application. Any suggestion otherwise violates our terms of service and may result in immediate order cancellation and permanent account ban.
• No Medical Claims: No medical, therapeutic, pharmaceutical, or psychoactive claims are made or implied. This product is not a drug, medicine, dietary supplement, food additive, or cosmetic ingredient.
• Age and Legal Capacity: You are at least 18 years of age (or the age of majority in your jurisdiction, whichever is higher) and possess full legal capacity to enter into this transaction.
• Compliance with Laws: You are solely responsible for researching, understanding, and complying with all local, state, national, and international laws governing the import, possession, handling, storage, and disposal of AL-LAD and related lysergamide derivatives. The legal status of AL-LAD varies significantly by jurisdiction. AL-LAD is unscheduled in many countries but is explicitly controlled in others. Some nations have generic analogue legislation (e.g., US Federal Analogue Act, Canadian CDSA analogue provisions, German NpSG for certain tryptamines/lysergamides, UK Psychoactive Substances Act). RChems EU does not provide legal advice. We strongly recommend consulting with local legal counsel before ordering.
• Export/Import Authorization: You are responsible for obtaining any required import permits, licenses, or authorizations. RChems EU ships on an Ex-Works (EXW) or Delivered-at-Place (DAP) basis depending on destination; title and risk transfer upon dispatch. Customs clearance is the buyer’s responsibility.
• Restricted Regions: RChems EU reserves the right to cancel, refund, or refuse any order from regions where lysergamides or their analogues are explicitly prohibited, including but not limited to: Australia, Sweden, Norway, Germany (under NpSG for certain lysergamides), Finland, and any jurisdiction where AL-LAD is specifically scheduled. Our website may geo-block certain regions. We do not ship to countries with blanket bans on research chemicals or where import of unscheduled chemical reference standards is prohibited.
• Liability Waiver: By completing your purchase, you release RChems EU, its owners, employees, and affiliates from any and all liability arising from misuse, improper handling, storage, disposal, non-compliance with local laws, or any other use not explicitly authorized in these terms.
• No Refunds for Seizure: Due to the nature of research chemicals and varying international customs enforcement, we cannot offer refunds or replacements for orders seized by customs where the buyer failed to verify local legality or secure necessary permits. We offer reshipment policies exclusively for documented delivery failures (not customs seizure) at our discretion.

FAQ Section

1. What is AL-LAD used for in research?

AL-LAD (6-Allyl-6-nor-lysergic acid diethylamide) is a lysergamide analogue used to study serotonin 5-HT2A receptor structure-activity relationships. Unlike LSD (which has an N6-methyl group), AL-LAD features an N6-allyl group (-CH₂-CH=CH₂). Researchers employ AL-LAD L-tartrate Pure in receptor binding assays (determining Ki values across serotonin receptor subtypes), functional GPCR studies (measuring calcium flux, IP3 accumulation, β-arrestin recruitment), metabolic stability assays (comparing N-dealkylation rates to LSD and ETH-LAD), and SAR comparisons across the N6-alkyl lysergamide series (methyl, ethyl, allyl, propyl, cyclopropylmethyl). It is strictly a research tool—not for human or veterinary use.

2. Is AL-LAD L-tartrate legal to buy online?

The legal status of AL-LAD for research varies significantly by jurisdiction. In the United States, AL-LAD is not explicitly listed in the Controlled Substances Act (CSA) schedules, but the Federal Analogue Act may apply if the product is intended for human consumption. In the European Union, laws differ by country: some countries regulate lysergamides under generic analogue legislation (e.g., Germany’s NpSG covers certain lysergamides), while others have no specific scheduling. Some countries (e.g., Australia, Sweden, Norway) have explicitly banned AL-LAD or its analogues. RChems EU sells AL-LAD L-tartrate strictly as a research chemical for laboratory use. Buyers are solely responsible for verifying local laws before ordering. We do not ship to Australia, Sweden, Norway, or other jurisdictions where lysergamide analogues are explicitly banned. Please consult local legal counsel.

3. How discreet is your shipping for AL-LAD L-tartrate?

Extremely discreet—our StealthShield™ Pro protocol is among the most advanced in the research chemical supply industry. Your AL-LAD L-tartrate Pure order arrives in plain, unbranded outer packaging with no company logo, no chemical name, and no mention of “research chemical” anywhere on the exterior. The return address uses a generic logistics name (e.g., “LC Distribution”). Customs declarations use vague, non-alarming descriptions such as “Laboratory reagent sample for analysis” or “Inert crystalline solid for R&D.” Inside, the amber glass vial is vacuum-sealed inside an opaque, multi-layer foil pouch. No third party—postal workers, customs officers, or neighbors—will be able to identify the contents. This ensures complete confidentiality for academic, pharmaceutical, forensic, and industrial researchers.

4. What is the exact purity level of your AL-LAD L-tartrate?

Our AL-LAD L-tartrate Pure consistently tests at ≥99% purity by HPLC-DAD (area normalization at 254 nm with three-wavelength confirmation). The remaining <1% comprises trace residual solvents (ethanol, ethyl acetate, each <0.3% by GC-FID) and water (<1% by Karl Fischer coulometric titration). No undeclared adulterants, cutting agents, isomeric impurities (e.g., iso-AL-LAD, lumi-AL-LAD), synthetic intermediates, or degradation products are present above 0.5%. The compound is supplied as the authentic hemi-L-tartrate salt (1:0.5 molar ratio of AL-LAD freebase to L-tartaric acid), confirmed by ¹H NMR integration.

5. How do you test the purity of AL-LAD L-tartrate?

We perform seven independent analytical tests on every batch before release:
(1) HPLC-DAD (purity ≥99%, three UV wavelengths),
(2) ¹H and ¹³C NMR (structural confirmation and 1:0.5 salt stoichiometry),
(3) HRMS-ESI or HRMS-TOF (exact mass verification <3 ppm),
(4) Karl Fischer coulometry (water content <1%),
(5) Residual solvent analysis by GC-FID headspace (ICH Q3C compliance),
(6) Heavy metals screening by ICP-MS (Pb, As, Cd, Hg, Ni below 1 ppm),
(7) Optical rotation (polarimetry) (confirms natural ergoline stereochemistry, ruling out racemization).
A Certificate of Analysis (COA) summarizing all seven test results, including chromatograms and spectral data summaries, is available by batch number. This rigor ensures that when you buy 99% pure AL-LAD L-tartrate from RChems EU, your research is based on a fully characterized, high-integrity compound.

6. Can I track my AL-LAD L-tartrate shipment internationally?

Yes. All orders receive a discrete tracking number via encrypted email within 24–48 hours of dispatch. You can monitor progress from our warehouse through your local delivery hub (USPS, Royal Mail, DHL Express, Deutsche Post, La Poste, PostNL, Canada Post, Australia Post, Japan Post, etc., depending on region). The tracking portal displays only “Shipment in transit” and estimated delivery dates—no product details, no chemical names, no reference to RChems EU or “research chemical.” For maximum privacy, we recommend using an institutional address (university department, research institute mailroom) or a trusted commercial receiving point. We do not require signature on delivery unless specifically requested.

7. How should I store AL-LAD L-tartrate for long-term research?

Store AL-LAD L-tartrate Pure in its original amber glass vial with the PTFE-lined or phenolic screw cap tightly sealed. Keep at 2–8°C (standard laboratory refrigerator). Do not freeze, as freeze-thaw cycles may induce crystal lattice changes or promote condensation upon thawing. Place a desiccant packet (silica gel, indicating type recommended) inside the outer container if storing for >6 months. Allow the vial to reach room temperature (approximately 20–30 minutes out of the refrigerator) before opening to prevent condensation of atmospheric moisture on the cold powder. Minimize headspace; consider transferring to a smaller, argon-flushed amber vial if the original container is only partially filled. Under these conditions, the compound remains chemically stable (≥99% purity, no detectable degradation by HPLC) for at least 18 months. For archival storage beyond 18 months, consider -20°C in a non-frost-free freezer with desiccant, but allow slow warming before opening.

8. Why choose the L-tartrate salt over freebase AL-LAD?

The L-tartrate salt offers three critical advantages over the freebase form: (1) Superior aqueous solubility (>5 mg/mL in deionized water vs. <0.2 mg/mL for freebase), which is essential for preparing stock solutions in physiological buffers (PBS, HEPES, Tris) and cell culture media without requiring organic co-solvents (DMSO, ethanol) that can interfere with biological assays or affect cell viability. **(2) Non-hygroscopic handling**—the crystalline salt does not clump or absorb atmospheric moisture during weighing, improving gravimetric accuracy on microbalances (±0.01 mg precision). **(3) Enhanced thermal stability** (decomposition temperature >185°C vs. <140°C for freebase), allowing for room-temperature handling during short experiments without degradation. For researchers conducting receptor binding assays, functional calcium imaging, or metabolic stability studies, the L-tartrate salt is the preferred formulation.

9. How does AL-LAD compare to LSD and ETH-LAD in research?

AL-LAD, LSD, and ETH-LAD differ specifically at the N6 position (the indole nitrogen):

• LSD: N6-methyl group (smallest, least steric bulk).
• AL-LAD: N6-allyl group (-CH₂-CH=CH₂) – introduces unsaturation and moderate steric bulk.
• ETH-LAD: N6-ethyl group (-CH₂-CH₃) – saturated, intermediate steric bulk.

These modifications produce measurable differences in receptor binding affinity, functional selectivity (bias), and metabolic stability in vitro. Published SAR research suggests that the N6-allyl group of AL-LAD alters the kinetics of 5-HT2A receptor interaction compared to the N6-methyl of LSD and the N6-ethyl of ETH-LAD. AL-LAD is thus an essential reference compound for researchers systematically mapping the N6 substitution tolerances of serotonin receptors and for understanding the relationship between N6 alkyl structure and G-protein vs. β-arrestin signaling bias.

10. Do you offer bulk quantities of AL-LAD L-tartrate for institutional research?

Yes. While we routinely supply research quantities (250 mg, 500 mg, 1 g, and 2 g vials) for individual laboratories and independent researchers, RChems EU can accommodate larger bulk requests (5 g, 10 g, 25 g, and custom quantities) for established research institutions, contract research organizations (CROs), pharmaceutical companies, and forensic laboratories with appropriate institutional approvals. Please contact our encrypted support channel (ProtonMail compatible) for custom quantity pricing, batch reservation, lead time estimates, and supply agreements. All bulk orders undergo the same rigorous seven-test analytical characterization as our standard vials and are shipped with the same discreet StealthShield™ Pro packaging protocols. Multi-batch homogeneity testing is available upon request.

Advance your lysergamide structure-activity research with uncompromising quality and discretion. Order AL-LAD L-tartrate Pure from RChems EU today and experience the global standard in 99% purity, proven discreet worldwide delivery, and full analytical transparency. Buy AL-LAD L-tartrate online with confidence—only from RChems EU.