3-MMC (3-Methylmethcathinone)

Buy 3-MMC Research Chemical Online – USA, Europe & Worldwide

The substituted cathinone class of research chemicals has garnered significant attention in neuropharmacology due to their structural similarity to naturally occurring cathinone and their potent interactions with monoamine transporters. 3-MMC (3-Methylmethcathinone) is a synthetic cathinone derivative characterized by a beta-keto phenethylamine backbone with a methyl group at the 3-position of the phenyl ring and an N-methyl substitution on the ethylamine side chain. This specific structural configuration—a ketone at the beta position and a 3-methylphenyl ring—confers distinct pharmacological properties compared to other cathinone derivatives, including the more widely studied 4-MMC (mephedrone).

The compound is registered under CAS number 1246816-62-5, providing unambiguous chemical identification for research documentation. For researchers investigating the molecular mechanisms of monoamine transporter interactions and the structure-activity relationships of synthetic cathinones, 3-MMC offers a valuable tool to explore how methyl group position (3- vs. 4-substitution) influences dopamine (DAT), norepinephrine (NET), and serotonin (SERT) transporter binding and releasing activity. When you buy 3-MMC from RChems EU, you acquire a high-purity research compound manufactured under strict quality controls. Our 99% pure 3-MMC is intended exclusively for laboratory research—not for human or animal consumption—enabling precise, reproducible experiments in receptor pharmacology, neurochemistry, and behavioral neuroscience.

Key Features & Benefits

• Verified 99%+ Purity: Every batch undergoes independent HPLC, LC-MS, and ¹H/¹³C NMR analysis to guarantee ≥99% purity.
• Substituted Cathinone Derivative: Enables SAR studies on beta-keto phenethylamines and their interactions with monoamine transporters.
• 3-Methyl Phenyl Substitution: The methyl group at the 3-position allows comparison with 4-MMC (mephedrone) and other ring-substituted cathinones.
• Monoamine Transporter Research Tool: Investigates dopamine (DAT), norepinephrine (NET), and serotonin (SERT) reuptake inhibition and releasing mechanisms.
• CAS-Identified Compound: Registered under CAS number 1246816-62-5 for unambiguous chemical identification.
• Well-Defined Physical Properties: Characterized by melting point (209-210°C) and molecular formula (C₁₁H₁₅NO).
• Worldwide Delivery: Fast, tracked shipping to the USA, Canada, Europe, Australia, and select Asian research hubs.
• Discreet Packaging Protocol: Plain outer boxes, unmarked labels, vacuum-sealed inner bags—no chemical names on the parcel.

Product Specifications

Applications & Usage

⚠️ Strictly for laboratory research use only. Not for human or animal consumption.

3-MMC is utilized in a range of non-clinical, pre-clinical, and basic science research applications. Typical areas of investigation include:

• Monoamine Transporter Binding Assays: Evaluating affinity (Ki) for dopamine transporter (DAT), norepinephrine transporter (NET), and serotonin transporter (SERT) using radioligand displacement (e.g., [³H]WIN 35,428 for DAT, [³H]nisoxetine for NET, [³H]citalopram for SERT) in transfected cell lines or synaptosomal preparations.
• Neurotransmitter Release vs. Reuptake Inhibition Studies: Determining whether 3-MMC acts primarily as a monoamine releaser or reuptake inhibitor using in vitro superfusion or microdialysis techniques.
• Structure-Activity Relationship (SAR) Investigations: Systematically comparing 3-MMC with 4-MMC (mephedrone), 2-MMC, 3-CMC, and other ring-substituted cathinones to map the impact of methyl group position and halogen substitution on transporter selectivity, potency, and efficacy.
• Metabolic Stability Research: Evaluating phase I metabolism using hepatic microsomes or S9 fractions with LC-MS/MS quantification, particularly studying ketone reduction, N-demethylation, and aromatic hydroxylation pathways.
• Analytical Reference Standard: Serving as a high-purity calibrant for forensic toxicology, wastewater analysis, or novel psychoactive substance (NPS) screening methods.
• In Vitro Neurotoxicity Screening: Assessing cytotoxicity, mitochondrial function, and oxidative stress markers in neuronal cell cultures (e.g., SH-SY5Y, primary cortical neurons).

Researchers are encouraged to consult peer-reviewed literature (e.g., Journal of Medicinal Chemistry, Neuropharmacology, European Journal of Pharmacology, Drug Testing and Analysis) for established in vitro protocols. RChems EU does not provide research protocols but guarantees the compound’s structural integrity and purity for such applications.

Purity & Testing

Reproducibility in monoamine transporter research and neuropharmacology depends critically on compound purity. Impurities—particularly other cathinone isomers, synthetic intermediates, or degradation products—can produce false-positive signals in transporter binding assays or confound functional release measurements. That is why 99% pure 3-MMC from RChems EU is subjected to a multi-laboratory quality control workflow:

1. High-Performance Liquid Chromatography (HPLC-DAD): Quantitative analysis at multiple wavelengths. Minimum acceptance criterion: ≥99.0% peak area purity.
2. Liquid Chromatography-Mass Spectrometry (LC-MS): Confirms molecular ion [M+H]⁺ = 178.1 and detects trace-level organic impurities down to 0.05%.
3. Nuclear Magnetic Resonance (NMR): Both proton (¹H) and carbon-13 (¹³C) NMR verify the correct beta-keto phenethylamine backbone, 3-methyl substitution pattern on the phenyl ring, and N-methyl group. Any spectral deviation—particularly signals indicative of incorrect substitution (e.g., 2- or 4-methyl isomers)—triggers batch rejection.
4. Residual Solvent Analysis (GC-MS): Ensures compliance with ICH limits for Class 2 and Class 3 solvents.
5. Heavy Metal Testing (ICP-MS): Confirms levels below 20 ppm for lead, arsenic, cadmium, and mercury.

Each batch is assigned a unique lot number, and a Certificate of Analysis (COA) is available upon request. This rigorous testing ensures that when you buy 3-MMC for research, you receive a compound that performs consistently from order to order.

Safety & Handling Guidelines

⚠️ FOR LABORATORY RESEARCH USE ONLY. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

• Personal Protective Equipment (PPE): Always wear nitrile gloves, a lab coat, and chemical splash goggles when handling 3-MMC powder.
• Engineering Controls: Use a certified chemical fume hood or glove box to prevent inhalation of airborne particulates.
• First Aid Measures:
  • Inhalation: Remove to fresh air. If breathing difficulty persists, seek medical attention.
  • Skin Contact: Wash with soap and copious water for 15 minutes. Remove contaminated clothing.
  • Eye Contact: Rinse cautiously with water for 15 minutes. Consult an ophthalmologist if irritation persists.
  • Ingestion: Do NOT induce vomiting. Rinse mouth and seek immediate medical attention.
• Spill Management: Vacuum or sweep gently (avoid generating dust). Collect in a sealed, labeled container for hazardous waste disposal.
• Storage: Store in a tightly sealed, amber glass vial at room temperature (20–25°C) in a desiccator, protected from light and moisture.

By purchasing from RChems EU, you confirm that you are a qualified researcher (or authorized agent) and that your facility can handle this compound safely.

Global Shipping & Discreet Delivery

RChems EU has perfected a discreet, reliable global logistics system for all research chemical orders, including 3-MMC. We understand that confidentiality is essential for many academic and private research organizations.

What discreet delivery means for you:

• Plain Outer Packaging: Your order arrives in a non-descript padded envelope or small cardboard box. No logos, no brand names, no chemical identifiers.
• Unmarked Shipping Label: The return address uses a generic name (e.g., “L.C. Distribution” or “WH Logistics”). No reference to “RChems EU” or “3-MMC.”
• Vacuum-Sealed Inner Bags: Each bag is heat-sealed to prevent leakage, odor, and tampering. No chemical name appears on the inner bag.
• No External Documentation: Invoices, COAs, or packing slips are sent via encrypted email only—never placed inside the parcel.

Fast worldwide delivery times (tracked):

Every shipment includes a real-time tracking number. Expedited courier options (FedEx Priority, DHL Express) are available at checkout for faster delivery (2–5 days globally).

Why Choose RChems EU?

• Stealth Packaging Experts: Over 7,000 successful shipments to 45+ countries with minimal customs interference.
• Third-Party Verified Purity: Every batch is independently tested. We do not sell unverified or “research grade” material without documentation.
• Responsive Scientific Support: Technical inquiries answered within 24 hours. Replacement policy for lost or damaged shipments (terms apply).
• No Minimum Order Quantity (MOQ): Order 10 grams or 1000 grams—same meticulous packaging and quality standards.
• Flexible Payment Methods: Secure cryptocurrency (BTC, ETH, USDT) and select credit card options.
• Global Compliance Awareness: We monitor international regulations and adjust shipping policies accordingly.

Legal & Safety Disclaimer

⚠️ IMPORTANT – READ CAREFULLY BEFORE PURCHASING

3-MMC (3-Methylmethcathinone) is sold by RChems EU strictly as a research chemical and is not for human consumption, animal testing, or any form of in vivo use without appropriate institutional ethical approval. This product is not a pharmaceutical, medicinal product, dietary supplement, or recreational substance.

Legal Status Varies by Jurisdiction: 3-MMC may be a controlled substance or regulated analog in certain countries, states, or territories. In the United States, it may be considered a controlled substance analogue under the Federal Analogue Act (21 U.S.C. § 813) if intended for human consumption. Several European countries have specific analogue legislation or blanket scheduling for substituted cathinones. It is your sole responsibility to verify the legal status of 3-MMC in your country, state, or province before ordering.

By completing your purchase, you certify that:

1. You are at least 18 years of age.
2. You are a qualified researcher affiliated with a bona fide laboratory or academic institution.
3. You will use this product exclusively for lawful, laboratory-based research purposes.
4. You will not introduce this compound into the body of any human or animal.

RChems EU reserves the right to cancel any order that appears destined for non-research use or for a jurisdiction where 3-MMC is prohibited.

FAQ Section

1. What is 3-MMC used for in research?

3-MMC (3-Methylmethcathinone, CAS 1246816-62-5) is used in neuropharmacological research to study monoamine transporter interactions (dopamine, norepinephrine, and serotonin transporters), the effects of ring substitution position (3- vs. 4-methyl) on cathinone pharmacology, and structure-activity relationships among substituted cathinones. Typical applications include radioligand binding assays, neurotransmitter release studies, and metabolic stability research.

2. Is 3-MMC legal to buy and possess for research?

Legality depends on your jurisdiction. 3-MMC is not explicitly scheduled at the US federal level but may be considered a controlled substance analogue under the Federal Analogue Act (21 U.S.C. § 813) if intended for human consumption. Many European countries have analogue legislation or specific scheduling for substituted cathinones. You must check your local regulations before ordering. RChems EU ships on the condition that you assume full legal responsibility.

3. How discreet is the shipping from RChems EU?

Extremely discreet. All 3-MMC orders are shipped in plain, unmarked packaging with no external branding. The shipping label uses a generic return address. Inner bags are vacuum-sealed with no chemical names or CAS numbers visible. Our stealth protocol has enabled successful deliveries to over 45 countries with a 99%+ success rate.

4. What is the guaranteed purity level of your 3-MMC?

Every batch of 3-MMC from RChems EU is independently tested to be ≥99% pure via HPLC-DAD, with confirmation by LC-MS and ¹H/¹³C NMR. A lot-specific Certificate of Analysis (COA) is available for every order upon request.

5. How is the 99% purity tested?

We employ a five-tier analytical protocol:

• HPLC-DAD for quantitative purity (≥99% peak area at multiple wavelengths).
• LC-MS for molecular weight confirmation ([M+H]⁺ = 178.1) and trace impurity detection down to 0.05%.
• ¹H and ¹³C NMR for structural confirmation (beta-keto phenethylamine backbone, 3-methyl substitution pattern on the phenyl ring, N-methyl group).
• GC-MS for residual solvent analysis (ICH compliance).
• Heavy metal testing (ICP-MS) to confirm levels below 20 ppm.

All testing is performed by an ISO 17025-accredited contract laboratory.

6. Can you ship 3-MMC to my country (USA, UK, Germany, Australia, Canada)?

RChems EU ships 3-MMC worldwide, including the USA, Canada, United Kingdom, Germany, France, Italy, Spain, Netherlands, Switzerland, Norway, Australia, and New Zealand. However, due to varying legal statuses of substituted cathinones, we strongly recommend contacting our support team before ordering if you are located in Germany, Sweden, Finland, or any country with broad analogue legislation. For countries with strict import controls (e.g., Japan, Singapore, South Korea), we do not currently ship 3-MMC.

7. How should I store 3-MMC after delivery?

Store 3-MMC in a tightly sealed, amber glass vial at room temperature (20–25°C) in a desiccator, protected from light and moisture. For long-term storage (>6 months), refrigeration at 4°C under inert atmosphere (argon or nitrogen) is recommended. Always allow the sealed container to reach room temperature before opening to prevent condensation.

8. What is the difference between 3-MMC and 4-MMC (mephedrone)?

The key structural difference is the position of the methyl group on the phenyl ring:

• 4-MMC (mephedrone) has a methyl group at the 4-position
• 3-MMC has a methyl group at the 3-position

In monoamine transporter research, the position of the methyl group significantly affects:

• Selectivity for DAT vs. NET vs. SERT
• Potency and efficacy as a monoamine releasing agent vs. reuptake inhibitor
• Metabolic stability and metabolic pathway profiles

Comparing these two positional isomers allows researchers to map the impact of methyl group position on cathinone pharmacology.

9. What is the mechanism of action of 3-MMC in research models?

In in vitro research models, 3-MMC acts primarily as a monoamine releaser and/or reuptake inhibitor, depending on the specific transporter. The beta-keto group (characteristic of cathinones) distinguishes this class from non-ketone amphetamines. Researchers determine the specific mechanism (release vs. reuptake inhibition) using functional assays in transfected cell lines or synaptosomal preparations. The 3-methyl substitution influences the compound’s selectivity profile compared to 4-substituted analogs.

10. What is the significance of CAS number 1246816-62-5?

CAS number 1246816-62-5 is the unique Chemical Abstracts Service identifier for 3-MMC (3-Methylmethcathinone). Researchers can use this CAS number for precise chemical identification when ordering reference standards, searching scientific literature, or documenting research materials. It is the standard identifier across analytical chemistry, forensic toxicology, and pharmacological research.

11. Do you offer a reshipment policy if customs seizes my package?

Yes. RChems EU offers a one-time reshipment policy for confirmed customs seizures in most countries, provided that the original shipping address is valid and the buyer did not violate known local laws. Crypto payments qualify for the full reshipment guarantee. Terms and conditions apply—please contact customer support for details.

12. Can I get a Certificate of Analysis (COA) before ordering?

Absolutely. Contact our support team via email with the product name (3-MMC or 3-Methylmethcathinone) and your research affiliation. We will provide a redacted or full COA for the current batch, including HPLC chromatograms and NMR spectra, subject to verification of legitimate research intent.

Ready to advance your substituted cathinone and monoamine transporter research? Order high-purity 3-MMC from RChems EU today and experience unmatched product quality, stealth global delivery, and professional scientific support. Buy 3-MMC for Research

RChems EU – Your trusted global supplier of 99% pure research chemicals.